I would like to start a list of important clinical biomarkers impacted by rapamycin. I thought GFR and epigenetic age should be pretty high on the list since GFR is supposed to only go down with age and epigenetic DNA methylation biological aging goes up so improvements should be more correlated with rapamycin specific effect. Does anyone have others to add with values pre and post rapamycin? I measured GFR before starting rapamycin and after 6 months using both creatinine and cystatin-c biomarkers. I can say that my GFR went up from 83 to 111 after 6 months of rapamycin so I am pretty happy about that. I am also remeasuring epigenetic age using Elysium index soon so I expect that will also be informative. Did Elysium index methylation assay twice before starting rapamycin so should have a good pre-treatment baseline.
Currently taking 5mg rapamycin weekly with grapefruit juice and 75-100mg acarbose with meals. I also try to take rapamycin after volume depletion using IR sauna for 60-90minutes before dose.