I think floaters are similar in that if you can get homeostasis to work better floaters will gradually clear. I have photographs taken of my retinas every so often. I got a big floater and a few little ones before I got into biohacking. The little ones have gone. The big one is still there, but smaller. My view is that these things are part of the aging pathway and if cells function better which is a mixture of mitochondrial issues and senescence (although you can intervene directly on the pathway as well with pro acetyl-CoA and HDAC inhibitors.) then gradually these things get better. I can post the photos if people are interested. I took the view to get photos even though i don’t have actual visual impairment beyond myopia. I used to have a bit of hypermetropia but that has faded.
I had floaters after a viral infection for approximately 2 months. Then they completely disappeared on their own. It was 3-4 years ago.
I have occasionally noticed one or two “floaters”. (They seem to slowly move down from top to bottom…maybe they should be called “sinkers”? LOL)
Anyway, mine seem to disappear after a few weeks. Later on, a different one will appear. Then that disappears.
I am continuing this review process and it is clear that this is a reversible process. My optician is quite interested and spent some time trying really hard yesterday to see if there was any cloudyness in one of my eyes, but it is now totally clear. The other still has some. I think this makes it clear that if you fix the mitochondria lot of other things get fixed slowly. It cannot be immediate, but I will keep up the review procss.
I recently checked my eyes - no sign of cataracts yet. My grandparents and my mother had cataracts. Hope rapamycin will prevent it for me in the future.
Eye floaters = chronic infection. it looks like worms cause they are. i use castor eye drops to remove mine
What’s the source of your information?
Per Copilot:
Main Cause: Aging of the Vitreous
• Your eye contains a gel-like substance called the vitreous humor.
• As you age, this gel liquefies and shrinks, causing collagen fibers inside it to clump together.
• These clumps cast shadows on your retina, which you perceive as floaters
Mainstream healthcare have zero education in parasite (worm) infections. You can take ivermectin and poop out tons of dead worms and bring it to the hospital for analyze and the testing will show up as negative. None of the people in parasite groups are recomended to do mainstream testing, as its basically pointless
A good friend of mine researches crystallins (the proteins which make up the lens). Normally they are nice and aligned and your lens is transparent. When they’re damaged, they get mis-folded, you lose transparency, thus getting a cataract.
The lens has no blood flow and no protein turnover, so there’s no feasible mechanism for reversing it. A cataract is a physical object made of aggregated proteins. How is a small molecule going to disaggregate them and remove them? The lens does not even have a chaperone system to remove misfolded proteins.
In my (limited) experience with my parents and two dogs, doctors seem to like to say you’ll need to get cataracts sorted in the future, but they’re quite often wrong. Both my parents were told that many years ago, and neither has cataracts, and neither takes Rapamycin.
I’ll just add a little tidbit to your good explanation that I recently learned.
The floater is apparently when those clumps break off and is why you see them sometimes and not at others.
Also, our eye doc says floaters can be a warning sign that you are about to have a retinal detachment and he wants us to come in ASAP if we ever have one so he can make sure it’s nothing more than a floater (or if we see flashes). Probably overkill most of the time, but he sees it happen.
@relaxedmeatball fwiw, I just had my 59 yo eyes checked, and my doc said due to having zero signs of cataracts at this age, I’ll probably never have them. I was looking forward to new lenses!!!
IMO your generalization is inappropriate. If it’s just your opinion then say it. Otherwise provide info/link to support it.
My optician said in his experience people who have clouded lenses and diabetes can reduce the clouding by controlling the diabetes.
This does appear in the literature
https://www.ajo.com/article/S0002-9394(14)73929-7/abstract
Some turnover has been found in non-diabetics
Conclusions
As the first direct evidence of carbon turnover in protein from adult human nuclear fiber cells, this discovery supports the emerging view of the lens nucleus as a dynamic system capable of maintaining homeostasis in part due to intricate protein transport mechanisms and possibly protein repair. This finding implies that the lens plays an active role in the aversion of age-related nuclear (ARN) cataract.
The dose of rapamycin is very important; continue with the lowest possible dose. The risk of side effects increases as the dose increases. If 1 mg is sufficient, one mg per week will do the trick.
I don’t understand the reasoning for this?
Too low of a dose of Rapamycin provides little to no benefit as shown in the PEARL trial. I think you should use the highest dose that provides the least side effects. This will be different for everyone. For me, that is 10 mg a week (3 mg + GFJ + EVOO)
I don’t know about rapamycin and cataract prevention, but as an ophthalmologist, I have been aware for a long time that cataract formation is influenced by intraocular vitamin C levels. I have been supplementing with a minimum of 1 gram of vitamin C daily since age 16. I am now 74. Recent complete eye examination showed no evidence of cataract development for my lenses.
Although the AAO doesn’t recommend Vitamin C supplementation, I shall persist.
The OpenEvidence AI provides the following commentary, which at least partially supports my view.
Decreased concentration of vitamin C (ascorbic acid) in the ocular aqueous humor is associated with increased risk and severity of cataract development. Vitamin C is a major antioxidant in the aqueous humor, protecting lens proteins from oxidative damage, which is a key mechanism in cataractogenesis. Lower aqueous humor ascorbic acid levels correlate with greater lens opacification and higher cumulative dissipated energy during phacoemulsification, indicating more severe cataract. Observational studies and meta-analyses consistently show an inverse association between serum or aqueous humor vitamin C levels and the risk of age-related cataract, including nuclear, cortical, and posterior subcapsular subtypes.
Genetic studies further support a causal relationship: variants in the sodium-dependent vitamin C transporter gene that reduce intraocular ascorbate are associated with higher risk of cortical and posterior subcapsular cataracts. Mechanistically, vitamin C inhibits aggregation of lens crystallins, a process central to cataract formation, and can even reverse protein aggregation in vitro.
However, randomized controlled trials of vitamin C supplementation have not demonstrated a clear preventive effect. The American Academy of Ophthalmology (AAO) states that there is currently no high-quality evidence supporting vitamin C supplementation for cataract prevention, but maintaining adequate dietary intake of vitamin C is reasonable.
In summary, lower vitamin C concentration in the aqueous humor increases the risk and severity of cataract, but supplementation beyond dietary sufficiency is not currently recommended for prevention.
A great reason to take vitamin C. I take 1 g of extended release vitamin C every night.
What about some sort of vitamin C eyedrops?
I’m hesitant to take high dose antioxidants year round.
I’ve never Rx’d vitamin C eyedrops, but like any eyedrops, if available, it would likely come with some kind of preservative. You would rather not expose your conjunctiva / tear film to extra preservatives on a chronic basis.
So… if averse to 1 gram of Vitamin C, you could take a daily multivitamin like which would likely include a lower dose of Vitamin C
There is an argument with anti-oxidants like Vitamin C that if you take them too often this undermines the stimulation of NRF2 and production of endogenous anti-oxidants. I personally therefore take Vitamin C on two days a week.