Monday - Legs
Tuesday - Upper body
Wednesday - Rest day - Rapamycin dosing
Thursday - Rest day - Tirzepatide dosing
Friday - Legs
Saturday - Upper body
Sunday - Rest
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Can you share your dose and your objective for your training? Also the time of day of the workouts and the rapamycin dose?
Iāve run experiments with my training at different doses and have reached a different conclusion about the compatibility of rapamycin with hypertrophy trainingā¦ but I suspect itās because we have different objectives.
Edit: this is really the wrong thread for this conversation. We should probably move elsewhere.
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Thanks @AustraliaLongevity. Hereās where to follow the discussion: Does exercise really extend life? Finnish twin study - #90 by AustraliaLongevity
See also: Experience with GLP-1s
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I believe weāll see generic empagliflozin this year, at least in my country.
Brand name is about US$1/day, so itās not that bad anyways.
I take canagliflozin personally.
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Hopefully you share the results here. I use 10mg and wonder what would happen if I used 25mg. Do you plan to also get a urinalysis? (I pee +2 glucose all the time on 10mg). I would also wonder how it impacts your electrolyte panel and uric acid (if you test this), or anything else you notice that looks different compared to previous lab results.
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Yea I have read people say Reta doesnāt suppress their appetite much but that just makes me think they arenāt using a high enough dose where it would happen. I also think many used to use Tirzepatide, which seems to suppress appetite more so they are making the comparison. The paradox here is that Reta has shown greater weight loss than Tirz in the studies.
My own anecdote is that I got reduced appetite on 3mg so I cut back down to 2mg (divided MWF shots). This seems to be my sweet spot where I am still hungry but get full faster.
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FYI, generic empagliflozin is available at the Indian pharmacies.
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Yes it is, take it at your own risk. When I first bought empagliflozin from India, I did my usual procedure of putting in the same order to three different vendors, so that I increase the chance at least one will get through and if I lose one I have not lost too many meds. Anyhow, with one vendor (whom I no longer use), I forgot to specify the original manufacturer brand, and what I got from him was a generic. Well. The tablets looked discolored with random green yellowish patches, and I decided to discard them. I canāt claim they were ābadā, but between their dodgy appearane and the harrowing tales of quality control at Indian pharma manufacturers, I decided it was too much for my risk tolerance. It was my fault for not specifying, but I never made that mistake again. Now with the orders still coming in (hopefully before 08/29/25!), I will have completed my 5 year stash of brand name 25mg Jardiance - yes, Jardiance a few thousand dollars, but Health, well, is priceless. YMMV.
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Brand name 25 mg Jardiance.
I just received my Jardiance prescription through insurance - 25 mg ā 30 pills cost $50. I am doing a 7 day loadingā¦ then will go every other day. At that rateā¦ $300 a year. Not bad, and I am getting it directly from my pharmacy.
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Brilliant. Thatās actually cheaper than I get from India - I get them at $1 per tablet. I donāt care - I want the brand name whenever can.
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Every time I try even a half dose of dapagliflozin I get what feels like a mild urinary tract infection, but I test negative and itās gone within 5 days after stopping. I stay well hydrated. Has anyone else had and been able to solve this problem? I canāt take the drug anymore.
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Are you taking methylene blue? If so, that is supposed to help with that issue.
Iām taking MB and dapagliflozin.
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Hmm, I was at one point but I donāt know if I was the last time it happened. Good tip!
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Do you take MB daily and do you cycle?
Dose?
tks
Interestingā¦ I started Jardiance this week and was using MB every 3rd dayā¦ so far all good.
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If you have commercial insurance, you can get Jardiance for $10/mo with the manufacturerās co-pay coupon.
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If you have Medicare, you cannot use the coupon. Itās a raw deal for Medicare folks like my parents.
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My issue is with a lot of these things, I have to meet my out of pocket deductible first, and that is 8k
@Connie_Theron_Beidel My doc advised me to take it daily, so I did that for a long time, but recently I heard the people at Gethealthspan advise to skip it on the weekends, so that is now what I do.
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More evidence that SGLT2iās inhibit mTOR and activate AMPK:
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Did they give any reasons besides cost saving?
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