I just stumbled into this list of different people’s supplement / longevity regimens, by “Vincent Weisser at Molecule + VitaDAO with product, design and dev background exploring decentralized science and longevity.”
Perhaps some ideas people can use or find interesting…
and
Thanks! I’ll consider that.
There is also this one that consolidates supplement list for well-known people who are active in the aging field: https://fastlifehacks.com/
Could Alzheimer’s Stem From Infections? It Makes Sense, Experts Say - The New York Times.pdf (603.7 KB)
This is an older article, but the research has continued.
cara2023, You say you take Valacyclovir every day. That’s very interesting. What brand name do you use and at what dose and time of day? And, did your doctor recommend it or did you find it by research? Thanks.
It’s generic, and a South African brand. I take 400 mg in the am. A dose for active viral outbreak is much higher. After the shingles subsided, I asked my doc if I should take it prophylactically since I’m on immune suppressants and he agreed.
Do you plan to have a shingles vaccine eventually? I want to have it done this winter, but afraid (as usually) of potential side effects. Many meds give me negative reactions unfortunately.
I had the vaccine with no negative reaction - which I usually have with vacs, and am also sensitive to many meds. The vaccine can’t prevent a reactivation of VZV (shingles), I believe it just makes it much milder.
Shingles can be anything from mild to devastating: "Shingles in the eye can cause vision loss and other serious complications.
An elderly lady I know had this happen to her. It started near her left eye and spread. She lost her vision in that eye.
In the U.S. most insurance companies wouldn’t pay for it until fairly recent times. Now most insurance plans will pay for it. I had no or very mild symptoms from the vaccine, I don’t remember, but the experience of the lady I know certainly drove me to get the vaccine as soon as possible.
My arm ached for several days after both shots. Not debilitating, definitely noticeable.
I also know older folks who had horrific experiences with shingles so I got the vaccine early.
I saw his video from a month ago. Unless I’m mistaken he still takes apigenin, though he gets it straight from parsley and not liposomal supplement like I do. I think he is one of the ones who showed me why someone might inhibit cd38 for nad+. I also wonder if he was using liposomal nmn or just straight nmn? Its risky to use liposomal because there aren’t much studies (or any) on it, and some question the health of liposomal delivery. Apparently just taking straight nmn doesn’t do much good (Stanfield has a good new vid about this)
I probably have at least fifty different supplements on my shelves. I am usually taking 15-20 of them daily. It is a real battle to keep them down to a reasonable few. One of the things I try to do is ask myself from time to time: Why am I taking this?
Today I decided to review my reasons for taking Berberine and found out that it has some unusual properties that I was not aware of; mainly, its action on the mitochondria.
“The first time, we used molecular docking and dynamic of Berberine with UCP1 gene in this study and revealed therapeutic potential of Berberine via modulation of mitochondrial UCP1 gene.”
It also inhibits lipogenesis. So berberine supplementation is also a contributing factor to my low lipid levels. I was certainly unaware of this property. It also appears to have some anti-cancer properties.
“Berberine (BRB), an alkaloid with anti-hyperglycemic and hypolipidemic properties, was recently shown to inhibit cellular lipogenesis, and respiratory complex I activity, exerting antiproliferative activity against tumor cell lines and tumor xenotransplants7,8,9,10, through mechanisms involving mitochondrial functions”
https://www.tandfonline.com/doi/abs/10.1080/07391102.2021.2024255
https://www.nature.com/articles/s41598-020-73594-z
A guide to Berberine dosing:
“The optimal dose of BBR was 1 g/day for TG, TC, and weight, 1.8 g/day for insulin and HOMA-IR, and 5 g/day for HDL.”
“It requires a strict dosage regimen. Berberine has a short half-life of several hours — half the dose will be metabolized and eliminated from your system within a few hours. To keep blood levels stable and benefit from berberine, spread the daily dosage (up to 1.5 grams or 1,500 milligrams daily) throughout the day. Dr. Bradley recommends taking it three times a day before meals.”
Berberine for Weight Loss and Insulin Resistance – Cleveland Clinic)%20throughout%20the%20day.
Thanks. I have also heard it was an effective antimicrobial for shifting gut flora towards a healthy composition. I have started to skip my berberine dose when I take metformin (I’ll still take the breakfast berberine but skip the dinner dose if I’m taking metformin after dinner). I felt that my blood sugar was getting too low.
Hi, Apologies for the delay in getting back to @Leonard but it was a long weekend here in the UK.
My regime looks like this: 8 weeks MK-2866 at 12.5 mg per day followed by 4 weeks post-cycle therapy of Tamoxifen and then 4 weeks of pure down time.
Hope that helps. 
Why did you choose tamoxifen and not clomifene or enclomifene? Are there and benefits in using tamoxifen?
What are your results with MK 2866?
Tamoxifen has been shown to help separately for Multiple Sclerosis (which I have - long-term remission since Mavenclad):
Tamoxifen accelerates the repair of demyelinated lesions in the central nervous system
Also seems beneficial elsewhere, for example:
Long-term use of tamoxifen reduces the risk of dementia: a nationwide population-based cohort study
