CALERIE Trials: Long-term Caloric Restriction on DNA methylation of Biological Aging

Calen Ryan, Columbia University

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial Dr. Ryan is an Associate Research Scientist in the Columbia Aging Center Geroscience Core at the Mailman School of Public Health, Columbia University. His work sits at the intersection of evolutionary biology, medicine, and public health, integrating high-throughput epigenetic data with large, longitudinal datasets to explore the impact of reproduction, stress, and energy on biological aging. Dr. Ryan’s research has received support from institutions such as the National Science Foundation, the National Institute on Aging, the National Institute of Environmental Health Sciences, and the Natural Sciences and Engineering Research Council of Canada. His work has also been featured in popular media outlets, including The Washington Post, CNN, the BBC, NBC, and Time Magazine.

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Nature Aging paper

Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial

https://www.nature.com/articles/s43587-022-00357-y

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