multiple human epidemiological studies demonstrated that caffeinated coffee intake is associated with decreased risks of developing nonmelanoma skin cancer and melanoma. Each daily cup of caffeinated coffee is associated with 5% reduced risk of skin cancer. The cancer-preventive effect of caffeinated coffee is dose-dependent. People who drink 6 or more cups of caffeinated coffee per day showed ~30% reduced risk of skin cancer. Importantly, decaffeinated coffee has no such effects, indicating that caffeine is an active constituent for skin cancer prevention.
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