They’ve given away a lot of free credits to burn, so make some suggestions!
[eg many of the downstream metabolites of MEL]
you can screen with https://www.adaptyvbio.com/ next
you could always just test evolutionary couplings a la
tho be careful just about ipSAE, u also want "As agentic loops in therapeutics become all the rage, it’ll be increasingly valuable to think about what score you’re maximizing.
ipSAE is specifically good for prediction of positioning and alignment of residues at a protein-protein interface.
But what if you care about alternatives like interface quality metrics (pDockQ, LIS), developability properties (hydrophobicity, viscosity, solubility), or immunogenicity/tox?"