Bodybuilding Supplement Shown to Stave Off Dementia in Mice

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Two for the price of one - Build muscle and stave off cognitive decline - sounds tempting.

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I posted the wrong link before. Here are the correct ones.

Regarding norvaline, another “bodybuilding” supplement that indicate potential for dementia.

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This was interesting

In particular

Exposure of murine C2C12 myoblasts to millimolar concentrations of HMB led to an increase in global histone acetylation, as monitored by anti-acetylated lysine immunoblotting, while preventing myotube differentiation. In these effects, HMB resembled, although with less potency, the histone deacetylase (HDAC) inhibitor Sodium Butyrate. However, initial studies did not confirm a direct inhibitory effect of HMB on HDACs in vitro.

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