Two tests in the last six months. 3.3 and 3.6 mg/dl. High carb and plenty of red meat.
We are at N=3 now.
So far we have 2 data points with low uric acid: 1 high carbs/red meat and 1 low carbs/meat(including red)
And a data point with medium uric acid level and no red meat.
Currently the carbs seem irrelevant and red meat has a slight advantage.
Thatâs never going to be a high power study but itâs fun anyway. 
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Mine is quite high being around 5mg/dl (300 umol/L). I am an unusually heavy drinker for a biohacker although I donât drink every day. Today, for example, is a non-drinking day. Yesterday, however, I drank 3 pints of bitter and 4 cans of lager.
I do eat red meat although not masses, I would say I am mid range on carbs.
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John, not suggesting you should, but curious If youâve ever tried kudzu root when drinking. From memory it reduces conversion of alcohol, meaning you can reach and maintain an enjoyable merry state with lesser alcohol intake. People naturally drink less as a result ,(apparently)
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I have some somewhere, but have not tried it. I do take DHM and pantethine when drinking. Both help to reduce the negative effects.
I just checked my data. My uric acid fluctuates between 240 and 210umol/l. I I have regular measurements for few years, I have two checkups a year one in March second in September. Funny enough the lower number is September, where I spend two months by the sea where I eat mostly vegetarian diet with some 3-4 meals with fish/shellfish⌠I eat more fruit and less wheat. My winter diet is same, just that I live above bakery, so I eat more sourdough and less fish, more cheese and milk, and 3-4 meals that include poultry or red meat a week.
My macros stay mostly same. I eat around 90-100 grams protein, around 70 grams of fat, 250+ grams of carbs and eat around 2000-2100 calories/day with 10-15% CR.
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Interesting, SGLT2 inhibitors reduce uric acid:
- Uric acid-lowering effects of sodium-glucose cotransporter 2 inhibitors for preventing cardiovascular events and mortality: A systematic review and meta-analysis 2024
- Effects of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on serum uric acid levels in patients with chronic kidney disease: a systematic review and network meta-analysis 2023
- Effects of empagliflozin on serum uric acid level of patients with type 2 diabetes mellitus: a systematic review and metaâanalysis 2023
- SGLT2 Inhibition and Uric Acid Excretion in Patients with Type 2 Diabetes and Normal Kidney Function 2022
(dapagliflozin and empagliflozin might be the best ones)
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So here are my urate figures
361 321 308 299 277 282 294 298 250 282 329.48 274 354.32 378.09 381.87 361.87 6% 358.4 360 350 340 300 375.14 higher because of beer over the weekend 369.83 343.74 308.34 308.78 310.04 320 316.33 298 306 350.04 297 310 316 287 301 320 316 308 330 310 297.7 340 315 310 320 340 a bit higher from drinking not a lot 344.7 no booze in prior week 350 perlmutter says keep below 297 umol/L 338.8 340 320 325 300 351.2 300 306.2 351.3 350 291.2 400 328.6 391.37 335 improved 305 330 370 318.7 287 314.2 350 306.3 348 333.1 320 316 317.2 299 301 302.7 350 286 310 330 328 330 301.3 355.3 311
Micromoles per litre.
I think it is relatively high because I drink a lot of alcohol. I have never had a gout issue. I was a much heavier drinker in the past say 20 years ago (like two bottles of red wine a night) and was not that well then, much that I was not normally ill enough to need medical attention.
My current (alcohol) stack is really good at minimising the effects of alcohol, but I think it (alcohol) probably pushes up urate.
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