Last week I started going to the Gym with my son. I did a blood test on Wednesday and it is quite surprising in one sense that AST has doubled from 24 to 48 and CK has massively jumped (from just around 100 to 920)
It strikes me that if people are regularly doing exercise given that these biomarkers hang around for a while you would need to stop going to the gym for some time to remove the impact.
I knew Creatinine was affected by exercise, but I was not aware of these two. Hence I thought I would post this.
CRP is very strongly increased by exercise as well. I did the first day of RAGBRAI with my college age son and he wasn’t just out for a ride, he was trying to kill me. It happened my blood was drawn the next day and my CRP was so bad the doctor just about had a heart attack. Normally my CRP is very low.
I think your body will get used to regular exercise and these markers will improve in spite of it. Exercise good, alcohol bad. Lol.
Good move! I expect the dramatic activity change was the key to the blood markers. I workout 4-5 days a week with a maximum 36-40 hours gap between my last workout and my blood draws.
This just means that you should postpone exercise for a week before taking any liver-related tests. There are no studies that I am aware of that associate exercise and liver damage.
“In this study, it has been shown that weightlifting resulted in profound increases in the liver function parameters, AST and ALT, as well as in LD, CK and myoglobin levels. Furthermore, we have been able to show that this effect was prolonged and that most subjects still had increased enzyme concentrations 1 week after performing the weightlifting programme.”
“The occurrence of idiosyncratic drug hepatotoxicity is a major problem in all phases of clinical drug development and the leading cause of postmarketing warnings and withdrawals [10]. Asymptomatic elevations of liver function tests during clinical trials could be drug-related, but other factors, such as strenuous exercise, have resulted in increased serum transaminase levels”
Muscular exercise can cause highly pathological liver function tests in healthy men
It was a surprise to me. It is well known, however. Because I do weekly blood tests I will probably just have to live with elevated figures for certain biomarkers.