There is a new textbook on the biology of aging that looks like a good read for anyone interested in a deep-dive into the longevity science.
Biochemistry and Cell Biology of Ageing: Part III
This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells.
The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed.
The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
For people who can’t afford the $200 price, there might be a free download of this book here.
1 Introduction: Progression of the Science of Ageing
Vera Gorbunova and Andrei Seluanov
2 Chromatin Structure from Development to Ageing
Lorelei Ayala-Guerrero, Sherlyn Claudio-Galeana, Mayra Furlan-Magaril, and Susana Castro-Obregón
3 The Nuclear Envelope in Ageing and Progeria
Adrián Fragoso-Luna and PeterAskjaer
4 Mitochondrial DNA Mutations and Ageing
Julia C. Whitehall, Anna L.M. Smith, and Laura C.Greaves
5 The Proteasome and Ageing
Ashok N. Hegde, Lindsey M. Duke, Logan E. Timm, and Hannah Nobles
6 Gap Junctions and Ageing
Michael J. Zeitz and James W. Smyth
7 Cellular Senescence and Ageing
Rebecca Reed and Satomi Miwa
8 Therapeutic Opportunities Presented by Modulation of Cellular Senescence
Richard G.A. Faragher, Neda Heidari, and Elizabeth L. Ostler
9 Ageing at Molecular Level: Role of Micro RNAs
Sanjay Yadav, SanaSarkar, Anuj Pandey, and Tanisha Singh
10 CircRNA and Ageing
Ebrahim Mahmoudi and Murray J. Cairns
11 Extracellular Vesicles and Cellular Ageing
Nekane Romero-García, Cristina Mas-Bargues, Javier Huete-Acevedo, and ConsueloBorrás
12 Fibrinogen, Coagulation, and Ageing
Rebecca Donkin, Yoke Lin Fung, and InduSingh
13 An Insight into Platelets at Older Age: Cellular and Clinical Perspectives
Guadalupe Rojas-Sanchez and Pavel Davizon-Castillo
14 Ageing Skeletal Muscle: The Ubiquitous Muscle StemCell
ClaireE.Stewart
15 Age-Related Changes in Central Nervous Systems - Hydroxytryptamine Signalling and Its Potential Effects on the Regulation of Lifespan
Sara Fidalgo and MarkS.Yeoman
16 Systems Biology of Ageing
Sharmilla Chandrasegaran, RebekahL. Scanlan, Peter Clark, Louise Pease, James Wordsworth, and Dary lP. Shanley
Note - Other books in this series also look interesting:
Biochemistry and Cell Biology of Ageing: Part I
Table of contents :
- Front Matter …Pages i-x
- Antioxidant Vitamins and Ageing (Irina Milisav, Samo Ribarič, Borut Poljsak)
- Autophagy: ‘Self-Eating’ Your Way to Longevity (Charlotte J. Pattison, Viktor I. Korolchuk)
- Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease (Simon C. Johnson)
- The Interplay Between Cholesterol Metabolism and Intrinsic Ageing (Mark Tomás Mc Auley)
- Key Age-Imposed Signaling Changes That Are Responsible for the Decline of Stem Cell Function (Melod Mehdipour, Yutong Liu, Chao Liu, Binod Kumar, Daehwan Kim, Ranveer Gathwala et al.)
- Creatine, Creatine Kinase, and Aging (Nathalie Sumien, Ritu A. Shetty, Eric B. Gonzales)
- Extracellular Matrix and Ageing (Helen L. Birch)
- Vitamin D and Ageing (Tom R. Hill, Antoneta Granic, Terence J. Aspray)
- Telomeres, Telomerase and Ageing (Gabriele Saretzki)
- Nuclear DNA Damage and Ageing (Kyriacos Agathangelou, Zisis Apostolou, George A. Garinis)
- Signal Transduction Pathways in Ageing (Cathy Slack, Jennifer Tullet)
- The Gut Microbiota and Ageing (Claire Maynard, David Weinkove)
- Nutrition and Ageing (Fiona C. Malcomson, John C. Mathers)
- Role/s of ‘Antioxidant’ Enzymes in Ageing (Elizabeth Veal, Thomas Jackson, Heather Latimer)
- B Vitamins and Ageing (Kathleen Mikkelsen, Vasso Apostolopoulos)
- Gene Expression, Epigenetics and Ageing (Babukrishna Maniyadath, Namrata Shukla, Ullas Kolthur-Seetharam)
- Glycobiology of Aging (Fabio Dall’Olio)
Biochemistry and Cell Biology of Ageing: Part II
Table of contents :
- Front Matter …Pages i-x
- Poor Early Growth and Age-Associated Disease (Jane L. Tarry-Adkins, Susan E. Ozanne)…Pages 1-19
- The Immune System and Its Dysregulation with Aging (Ludmila Müller, Svetlana Di Benedetto, Graham Pawelec)…Pages 21-43
- Pulmonary Diseases and Ageing (Peter J. Barnes)…Pages 45-74
- Neurodegenerative Diseases and Ageing (Lauren Walker, Kirsty E. McAleese, Daniel Erskine, Johannes Attems)…Pages 75-106
- Ageing and Cognition (Sydney M. A. Juan, Paul A. Adlard)…Pages 107-122
- Ageing and Osteoarthritis (Pradeep Kumar Sacitharan)…Pages 123-159
- Down Syndrome, Ageing and Epigenetics (Noémie Gensous, Claudio Franceschi, Stefano Salvioli, Paolo Garagnani, Maria Giulia Bacalini)…Pages 161-193
- The Vestibular System and Ageing (Sonja Brosel, Michael Strupp)…Pages 195-225
- Signal Transduction, Ageing and Disease (Lei Zhang, Matthew J. Yousefzadeh, Yousin Suh, Laura J. Niedernhofer, Paul D. Robbins)…Pages 227-247
- Skin Changes During Ageing (Frédéric Bonté, Dorothée Girard, Jean-Christophe Archambault, Alexis Desmoulière)…Pages 249-280
- Connective Tissue and Age-Related Diseases (Carolyn Ann Sarbacher, Jaroslava T. Halper)…Pages 281-310
- Potential Cellular and Biochemical Mechanisms of Exercise and Physical Activity on the Ageing Process (Mark Ross, Hannah Lithgow, Lawrence Hayes, Geraint Florida-James)…Pages 311-338
- Health Benefits of Anti-aging Drugs (Veronika Piskovatska, Olha Strilbytska, Alexander Koliada, Alexander Vaiserman, Oleh Lushchak)…Pages 339-392
- Visual Defects and Ageing (Sergio Claudio Saccà, Carlo Alberto Cutolo, Tommaso Rossi)…Pages 393-434
- Hutchinson-Gilford Progeria Syndrome: Challenges at Bench and Bedside (Ray Kreienkamp, Susana Gonzalo)…Pages 435-451
- Osteoporosis and the Ageing Skeleton (Terry J. Aspray, Tom R. Hill)…Pages 453-476
- Neurovascular Ageing and Age-Related Diseases (Raj N. Kalaria, Yoshiki Hase)…Pages 477-499