Wow that’s interesting. I use TRT cream which increases DHT. I’m also on 24mg of astaxanthin per night.
I actually just did a comprehensive blood test a few days ago that included DHT, I’ll be interested to see the results of this. I’ve never tested DHT before.
(2021) Astaxantin and Isoflavones Inhibit Benign Prostatic Hyperplasia in Rats by Reducing Oxidative Stress and Normalizing Ca/Mg Balancehttps://www.mdpi.com/2223-7747/10/12/2735 "We indicated higher testosterone levels in blood serum following finasteride and astaxanthin treatment, which could be explained by the inhibition of the 5a-reductase enzyme and less conversion of testosterone to DHT in prostatic epithelial cells, but the level of DHT was not assessed in our study. Serum testosterone elevations are known to occur with the administration of finasteride and dutasteride but the values typically remain within the normal laboratory range.
In the present study, both isoflavones and astaxanthin inhibited BPH development in rats with comparable efficacy with finasteride in terms of prostate weight, prostatic epithelium proliferation and prostate tissue cumulative histology score. However, only astaxanthin yielded a significant effect on epithelial area and testosterone level in blood compared to finasteride."
Stories like this remind me to take it easy on the exercise. I like my physique. I feel most of what I like about it, is that I lost body fat so that my muscle and veins show nicely. Most of that was lost from diet (and tirzepatide/berberine), not exercise.
No point suffering, if the suffering has nothing good on the other side.
Anecdotes always bring a form of bias. You didn’t compare the group of thriathletes as a whole compared with matched couch potatoes. The increase in Afib is significant though and as a result the increase risk of stroke, dementia, etc.
You always have to compare with something. Compare the overexercisers with the moderate intensity exerciser then and see what the risks and benefits are. That’s Afib at least which is significant. Anecdotes doesn’t help because you can have someone using the best method yet still end up in poor health and dying, or vice versa the worst method but the best health and life. In this case I don’t think it is the best method because of e.g Afib.
Many athletes, like Jim Fixx, who died unexpectedly, had underlying conditions that caused their deaths, not their sport or exercise.
It is the rare individual who over-exercises.
Personally I am in the moderation camp.
I dunno but I think 24mg at night every night is turning me a bit red lmao. People at work are asking if I’m ok. I’m doing fine and feel great and they don’t seem to know what I mean by “astaxanthin” and think I’m dying
AstaReal wins NutraIngredients-Asia Award for first clinical trial on children’s digital eye health
The recognition comes for conducting the world’s first clinical trial on digital eye health in children, with the study published in Advances in Therapy.
The trial demonstrated that astaxanthin supplementation can effectively reduce both chronic and acute digital eye strain whilst enhancing objective measures of visual performance.
In the clinical study, school-aged children received a daily dose of 4 mg of astaxanthin (AstaReal) for 84 days.
The findings indicate a significant improvement in chronic digital eye strain in the astaxanthin group compared with placebo, demonstrating a 20% greater reduction in the CVS (Computer Vision Syndrome) symptoms score by the end of the study.
The results also showed a 27% improvement in visual fatigue (acute digital eye strain) as well as improved stereopsis and pupillary light reflexes after the trial period.
Paper (paywalled):
Astaxanthin (AstaReal®) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial
Yeah, they pulled out a small change in one of the parameters. And the placebo group also seemed to get better over time too.
I thought lutein and zeaxanthin were the go-to for eye health, eye strain etc. Though Astaxanthin is a powerful antioxidant, so I guess it’s plausible to be helpful here.
Exactly correct. Lutein and zeaxanthin (and mesozeaxanthin) are most absorbed by tissues in the eye and most biologically significant. Astaxanthin is absorbed too, but to a much smaller extent, and doesn’t seem to do anything beyond what the former accomplish. I posted a ton of papers in various threads on all these carrotenoids and the eye.
I’ve read the 2019 safety review paper. While the maximum safe dose for natural astaxanthin seems quite high, I’m unsure about the safety of synthetic astaxanthin.
I know of people taking synthetic astaxanthin, such as Siim Land has been taking 24mg of synthetic astaxanthin daily for a year. Does anyone else have experience with synthetic astaxanthin?
I’m currently taking 3 ZanthoSyn capsules daily, which is 12mg * 3 = 36mg of synthetic astaxanthin. My liver enzyme levels are normal, but compared to the dosage for ITP, it seems insufficient. I plan to increase it to 12mg * 4 = 48mg. What are your thoughts, or are there any research papers I could refer to? Thank you.
I only did it for a week or two - then (because everything the Asta powder touched seemed to stain red, and I was concerned about my teeth) I stopped. I haven’t had time to devise a solution (e.g. encapsulation, etc.). It’s the Dutch company I sourced from. Synthetic. See this discussion: Astaxanthin, Natural vs. Synthetic - Your Thoughts?
