Another age clock interview

One more data point…

I’m still learning about all this… but recently listened to the Peter Attia podcast AMA on heart disease.

On Youtube: Peter Attia AMA 34 Heart Disease

His comments on this are:

How can CIMT (carotid intima media thickness) be helpful in understanding ASCVD?

  • CIMT is an ultrasound that’s done of the carotid arteries in the neck
  • Peter finds this to be a completely unhelpful test for a couple of reasons:
    • 1 – It is so user dependent in terms of the operator
    • The operator needs amazing technical skill to get a really good look at those carotid arteries
    • 2 – If you will want to see a change in this, you pretty much have to have the same person doing it again and again.
  • This might be that this is helpful if you have major, major carotid stenosis
    • Evenstill, Peter would still prefer to to a CTA in this situation
  • There are no guidelines that are based on a CIMT
  • People look to this test because it has no radiation, but the CAC has virtually no radiation

I don’t see an advantage of CIMT over CAC ”— Peter Attia

  • Interpreting results of CIMT can be confusing
  • A negative CIMT doesn’t tell much; it’s easy to miss things here
  • Obviously if there is a lot disease in the carotid artery, the CIMT will show it

Peter prefers a CAC over a CIMT

and

The CT angiogram (CTA) is a much better test

  • But it comes at a higher cost and it comes with more radiation
    • At really good places, it should be in the ballpark of 2 millisieverts of radiation
      • That’s a very small dose of radiation, about 4% of your annual allotted radiation, according to the NRC
  • A CT scan of the heart (this one is with contrast) captures the calcification
    • They typically run a dry scan first to look for calcium
    • But then once the contrast is in, you can see with great illumination the arteries
    • This gives a better sense of the luminal narrowing and the presence of soft plaque
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FWIW…

CIMT Test: A New Way to Look at Arterial Plaque

If you search “ford brewer cimt” on YouTube it should show his entire series about CIMT.

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Coronary artery calcification screening: estimated radiation dose and cancer risk

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