This is one of the things that piqued my curiosity about Prostaglandin E1
This was actually part of a study published in Science yesterday. Here’s the article overview.
Personally, I find the whole topic fascinating.
https://www.science.org/content/article/scientists-uncover-how-brain-washes-itself-during-sleep
Very cool!! I did read that article yesterday!!
And sleep is important to countering risk of Alzheimer’s disease [bold mine]:
Back in 2018, PET scanning was used to show that one night of sleep deprivation resulted in substantial increase in β-amyloid accumulation, in regions of the brain linked to Alzheimer’s disease. On a chronic basis, several studies have shown that poor sleep is prospectively linked to the risk and progression of Alzheimer’s disease. For example, in nearly 8,000 participants with 25-year follow-up, people aged less than 50 or 60 years with 6 hours of sleep or less had a >20% increased risk of developing late-onset dementia.