Unfortunately he also looks like he is 100 years old.
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He might have died though if he hadn’t started rapamycin. 
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Thank you for the well done interview. The bulleted note slides brought into the video were very helpful in following the interview.
I looked at some other interviews and presentations done with Dr. Green back to 2021 as well as looking at his website. His story telling seems consistent. Is there anything novel or new to your interview that you could point out?
I look forward to seeing your Matt Kaeberlein interview and some of the questions prompted here from RapNews.
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Sad to hear that you had a bad experience. Was it by email you didn’t get any response? In some cases emails end up in the spam filter and are hidden there. I have experienced this from other cases and got disappointed when I haven’t got any answer. My guess is that something like that can have happened.
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We all are going to age and look old but the lovely thing with Alan is that he has a great energy, passion and humour in life. So even if the outside looks old the inside seems much younger.
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Glad you like it and thanks for the feedback about the slides. It takes some time to create them but I think there is a value to it because it give a little bit extra deep to a podcast interview.
The extra interesting things that I take with me from the interview is:
- Dose regime differences based on different parameters
- Dose increase every decade was a interesting view
- His feedback on Matt Kaeberlein’s survey study
- When to ease up dose and when to start target dose directly
- His view that the longevity benefits will be larger in humans than in mice
Was it something that you would like me to have asked him? I’m going to have an second interview with him in the future so I’m open for suggestions regarding new questions.
Regarding Matt Kaeberleins interview it was almost 2,5 hour interview so I’m working on editing and creating slides on it. The interview was longer than I expected and there was many questions that I needed to cut out but I will have a second interview also with him in the future
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Agree that he was a little hard to understand, but I think a lot of that had to do with the quality of the recording, which was not as good as the first episode of this podcast.
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It’s possible, but a review from another patient on Healthgrades indicates I certainly am not the only one with these issues. Dr. Alan Green, MD - Forensic Pathology Specialist in Little Neck, NY | Healthgrades
I tried to get an appointment to see Dr. Green about 3.5 years ago but he never responded to emails or phone messages - so I gave up and ended up purchasing from India. I think he was a trailblazer when he started, and I applaud his efforts and how he’s helped the field, but I suspect he may not be the best doctor if you want more of a “hands-on” person to help deal with any complications, details,etc. I get the feeling he’s just overwhelmed… a lot of patients, and at his age why would he really want to work hard. There are lots of other doctors out there prescribing now, so you have many options: Rapamycin Prescription, Doctors that Prescribe It
@Krister_Kauppi , you may want to talk to some of the other doctors that are prescribing rapamycin and who are younger and more active in regular patient support and extensive testing… more along the lines of what Oliver Zolman is doing with Bryan Johnson (at a low level anyway).
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The slides are an excellent value and sync nicely with the presentation of the video. It makes your interview unique among others. I can imagine it taking a lot of time - but worth it for this viewer.
I appreciate the “extra interesting” things in the interview you have given. It is very good to have that pointed out.
I think Dr. Green’s aging journey is pretty remarkable. Not bad at all at 80 years old with his medical history. He gives off an easy sort of humor and seems pretty self-satisfied with how his medical practice has evolved - and he should be.
For a second interview, I would be interested in a follow-up to his assertion that his healthy patients are in some cases extraordinary athletes at the senior olympics level. He says that it is “mind blowing” as to what they are accomplishing under rapamycin. An extra interesting question might be to ask if rapamycin is a performance drug? (I don’t think it is like blood doping would be). In addition, what are the main attributes with using rapamycin that makes it possible to excel as an older athlete: heart function, ect?. Are his athletic patients dosing at a specific level of rapamycin for sports and do they take time off from rapamycin to enhance training before an event?
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I always found Dr. Green to be very responsive. Just make sure you are communicating with him via email. That’s the only way that works. I have never had a doctor spend three hours with me on a consultation with a flat fee. He did.
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Bad idea, age 25. I think age 35 or 40 is best due to my understanding of my readings from Blagosklony. Age 25 use would be like reducing the temp on a 60 minute cake at 45 minutes! Let the ‘cake’ first fully bake, and only then reduce the temp!
I’m age 69, taking this since 2018 and researched quite a bit. I’m Dr. Green’s 38 th patient.
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The brain is fully developed from 25-30 and since mTOR plays an important role in brain development I wouldn’t be so sure in stating that at 25 risk-benefit is really that clear as one of the last brain functions to fully develop (besides serotonergic system) is prefrontal cortex responsible also for good decision making 
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Mabe my recollection isn’t right, but the animals studies I have seen used lower doses starting younger for maximum life span. Green and Blagosklonny both seem to think you have to take higher doses when you are older.
If I had the opportunity to start rapamycin at age 25 I would do it. I just would use relatively low doses.
And with all due respect to Dr. Green, he has no idea or proof that 40 is the right age to start.
While I follow Dr.s Green and Blagosklonny they both occasionally express ideas that are just opinions that they can’t prove.
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The problem is that Rapamycin for longevity has only been ‘prevalent’ for the last few years. So, those individuals who have already experienced a great deal of aging already aren’t going to suddenly revert back to the health they had in their 20s. If Dr. Green was jumping around and running marathons, I think there’d be a lot more Rapamycin users!
The thing about Rapamycin is that it slows aging down (due to its autophagic effects?). It cleans up the body’s rubbish and makes us last longer. While it does have some instant health benefits for some users (like M. Kaberlein’s shoulder), most of us probably won’t see immediate benefits. However, if we are using Rapamycin over time, we should be able to compare ourselves with established benchmarks for age and after 5, 10, or 15 years, we should be operating at a more youthful level. That’s the hope anyways. We have to put our faith in the ITP and science. Also, if we are wrong, the downside (cost, canker sores, etc…) IMHO is not that negative. It seems it is a wager where the odds are stacked highly in our favour. I am going to be taking it for quite a while…
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I completely agree with your point of view, and think that taking this risk is worth it. Additionally, may I ask if you are currently taking acarbose or metformin? I am planning to start taking Rapamycin, but according to feedback on various forums, the main side effects are an increase in blood lipids and blood sugar. If this occurs, how should I handle it? Thank you.
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Yes, I take Metformin. I take 1 g 1 hour before Rapamycin as it helps absorption the same way GFJ does. Then I take 1 g the next two days. Then 500 mg the following 4 days. Then start over.
I eventually will add Acarbose. I just haven’t gotten it yet.
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Oliver Zolman and also Bryan Johnson would be great to interview. I have contact information to Oliver already but it has been hard to find to Bryan. Do you or anyone else have his contact information?
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One can do a lot of things at 25 to improve one’s decision making and brain health, I don’t really think rapamycin will inhibit that by a lot at that age. It’s like a drop in the sea compared to if a person isn’t really fit & exercising.
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You could try tweeting him or going through Oliver Zolman.
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