A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age

#1

Interesting but underwhelming. Impact of combo (low dose) supplement on biological age of older adults:

The daily dose of the supplement, supplied by Bayer Consumer Care AG, contained Vitamin D3 (20 µg), Vitamin B3 (niacinamide, 50 mg), Vitamin C (85 mg), Omega-3 polyunsaturated fatty acids (eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) acid, 250 mg), olive fruit extract (delivering 10 mg hydroxytyrosol), resveratrol (30 mg) and astaxanthin (3.2 mg).

3 Likes
#2

roughly 1/2 year reduction in epigenetic age over the course of the 12 week study, but p values were not significant (figure). P-values were significant for those with accelerated clocks or pace of aging (not shown here).

image
image847×558 114 KB

1 Like