6mg all on one day or spread throughout week?

This is a question for those of you who are taking 6mg (or thereabouts) per week.

Do you take it all on one day or do you spread it throuout the week?

Or do you do some other dosing pattern?

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Most people take it all in one dose, once per week. But i found starting at 1mg per week and the slowly increasing dose seemed to work well for me.

In other words I didn’t start dosing at 6mg per week right away, but worked up to that level.


Hi RapAdmin

Thank you very much indeed for your reply. It told me exactly what I wanted to know. :smile:

More info here if you want it: What is the Rapamycin Dose / Dosage for Anti-Aging or Longevity?


All in one day is key. You want to suppress mtorc1 as much as possible without suppressing mtorc2. mtorc2 isn’t affected until you chronic dose for a few days in a row and rapamycin builds up in your system.

So definitely the way to go is once a week or even once every other week.