Thank you for your effort! As for me, I prefer shorter versions - time is precious. Identifying 10 post-summary questions is plenty.
I very much like that this study shows that GLPs exert their rejuvenating effects through the hypothalamus.
This is the part of the brain that co-ordinates messaging with body in regards to glucose levels, oxygen, heat, cold etc. Hyperbaric oxygen studies have shown increased SIRT gene expression (? a longevity gene) in the hypothalamus, amongst other longevity benefits.
When elderly rats are given hypothalamic progenitor stem cells, they live longer and when their hypothalamus is damaged they die younger due to multi-organ failure.
I think there is a lot more positive research to come regarding the hypothalamus and am very glad that the possible GLP longevity benefits are been suggested to act through this important part of the brain.
Shorter summaries, please.
I find them useful and improved
I’ve been perusing the site tonight for the first time in several months and I immediately noticed the AI summaries. I like them a lot! Thank you rap admin
I thought about this topic when I heard my daughter talking about water usage from data centers. There are some videos debating this topic. I almost always get an AI response when I use Brave’s search engine. Here is what it stated:
AI Water Consumption
AI’s water usage is substantial and growing, driven by the energy demands of data centers that power large language models and other AI systems. Globally, data centers consumed about 560 billion liters of water annually in 2025, with projections rising to 1,200 billion liters by 2030 due to expanding AI infrastructure.
Per Data Center and Region
- A 100-megawatt U.S. data center, which uses more power than 75,000 homes, consumes approximately 2 million liters (528,000 gallons) of water per day—equivalent to the daily use of 6,500 households.
- Some large data centers use up to 5 million gallons (18.9 million liters) per day, comparable to the water needs of a town with 10,000 to 50,000 people.
Per AI Interaction
- Each 100-word AI prompt (e.g., to ChatGPT) is estimated to use 519 milliliters of water—roughly one standard water bottle—according to studies from the University of California, Riverside and The Washington Post.
- For a GPT-4 response, water use is estimated at 519 milliliters per 100 words, or about 3.5 milliliters per response based on energy use (1.75 watt-hours × 2 ml per watt-hour).
- GPT-3 inference for 10–50 queries consumes about 500 milliliters of water, depending on location and cooling methods.
Sources of Water Use
- Scope 1 (Onsite cooling): Water used directly in data centers for cooling servers via evaporative cooling towers or liquid cooling systems.
- Scope 2 (Power generation): Water consumed in generating electricity—thermal and hydroelectric plants account for most of this, especially in regions reliant on fossil fuels.
- Scope 3 (Supply chain): Up to 2,200 gallons (8,300 liters) of ultra-pure water are used to produce a single microchip.
Future Projections
- By 2027, AI’s annual water consumption could reach 4.2 to 6.6 billion cubic meters—equivalent to the annual water use of Denmark or half the UK’s total withdrawal.
- By 2028, AI data centers may consume 1,068 billion liters annually, according to a Morgan Stanley report.
Efforts to Reduce Impact
- Liquid cooling (direct-to-chip or immersion) reduces water use significantly compared to evaporative cooling.
- Use of recycled or non-potable water is increasingly common in drought-prone areas.
- Tech giants like Google and Microsoft are investing in water replenishment programs to achieve “water positive” operations by 2030.
Despite efficiency gains, the exponential growth of AI continues to strain global water resources, particularly in water-stressed regions. Transparency and sustainable cooling technologies are critical to managing this hidden environmental cost.
Just something to think about. I suppose if they built them near the ocean, they could use that water? I don’t know anything about that though.