Before mTOR modulation changes as we get older, how is mTOR modulated when it is optimal? - This may serve as a template for regulation with Rapamycin.
When does mTOR modulation go from optimal to suboptimal in the aging process?
Thank you for asking and have fun! My father grew up in Novato
Have there been significant advances in discrimination of senescent vs non-senescent cells or other improved procedures for measuring effect of senolytics?
Folks - since I’ll be at the Longevity Summit this coming Tuesday and Wednesday I’ll be asking researchers a lot of questions. If you have specific questions that might help us translate the research into actionable programs, please post your questions and I’ll try to get answers.
Here are the researchers who are presenting at the Longevity Summit:
Schedule below is in Pacific Time.
Tuesday12/06
8:00am - 8:40am
Breakfast & Networking Begins
8:45am - 8:50am
Opening Remarks- Dr. Christin Glorioso- Co-founder & CEO, NeuroAge Therapeutics, Longevity SF.
8:50am - 9:20am
Opening Keynote- Eric Verdin
9:25am - 9:45am
Morgan Levine
9:50am - 10:10am
Dr. Antoine Roux- Principal Scientist, Calico Life Sciences. “A Cell Atlas to Decipher Cell-type Aging”
10:15am - 10:35am
Sergio Ruiz
10:40am - 10:55am
Coffee break
10:55am - 11:15am
Dr. Hanadie Yousef - Co-founder & CEO, Juvena Therapeutics. “Harnessing the Regenerative Secretome of Human Pluripotent Stem Cells to Rejuvenate Tissues”
11:20am - 11:40am
Jennifer Garrison
11:45am - 12:05pm
Dr. David Weinkove- CSO, Assoc. Professor, Chair, Magnitude Bio, Durham U., BSRA & Dr. Marc Lucanic- CTO, GeroState Alpha. “Using C. elegans to find new drugs to slow aging”
12:05pm - 1:15pm
Lunch & Networking Break
1:15pm - 1:45pm
Opening Keynote- Dr. Spring Behrouz & Andy Lee- Founders, Vincere Biosciences. “The Path to Developing Selective Mitophagy Enhancing Small Molecules”
1:50pm - 2:10pm
Dr. Priyanka Joshi - Research Fellow, Co-founder, UC Berkeley, NeuroAge Therapeutics. “Targeting Aging to Treat Alzheimer’s Disease”
2:15pm - 2:35pm
Dr. Salah Mahmoudi- Assoc. Director, Alkahest. “Molecularizing the Science of Plasma to Therapeutically Target Diseases of Aging”
2:40pm - 3:00pm
Dr. Marco Quarta- Co-Founder and CEO, Rubedo Life Sciences. “Next Gen Senolytics for Selective Targeting Senescent Cell States to Treat Chronic Diseases of Aging”
3:05pm - 3:20pm
Coffee break
3:20pm - 3:40pm
Nathan Cheng - Director, GP, Founder, ODLB, Healthspan Capital, Longevity List. “The State of Longevity (2022)”
3:45pm - 4:05pm
Dr. Todd Haim- Director of NIA’s Office of Strategic Extramural Programs. “NIA’s Efforts to Foster Diversity in Aging Research and Entrepreneurship”
4:10pm - 4:30pm
Dr. James Peyer- CEO and Co-founder, Cambrian Bio. “Moving Beyond Generics and Supplements in Developing Healthspan-extending Medicines”
4:35pm - 5:05pm
Investors Panel- Maryanna Saenko, Ole Mensching, Max Unfried
5:05pm - 7:00pm
Wine and Hor D’oeuvres- Buck Institute
Wednesday12/07
8:00am - 8:40am
Breakfast & Networking Begins
8:45am - 8:50am
Opening Remarks- Dr. Christin Glorioso- Co-founder & CEO, NeuroAge Therapeutics, Longevity SF.
8:50am - 9:20am
Opening Keynote- Dr. Matt Kaeberlein- Professor, University of Washington, CSO, Optispan Geroscience. “The Dog Aging Project: A Template for Companion Animals in Geroscience”.
9:25am - 9:45am
Celine Halioua
9:50am - 10:10am
Dr. Ashley Zehnder- Co-founder & CEO, Fauna Bio. “Hibernation: A Survival Strategy Giving us Clues to Human Longevity”
10:15am - 10:35am
Dr. Marina Martinić Kavur- Head of R&D, GlycanAge. “Turning Back the Glycan Clock”
10:40am - 10:55am
Coffee break
10:55am - 11:15am
Dr. Tim Peterson - Professor, WashU. “The Chemistry that Unites Infectious Disease and Aging.”
11:20am - 11:40am
Dr. Oki O’Connor- Co-Founder and CEO of Scientific Affairs, Cyclarity Therapeutics. “A New Class of Drugs for Removing Toxic Biomolecules that Accumulate with Age”
11:45am - 12:15pm
Media Panel- Stephanie Dainow, Chris Patil, Allison Duettmann
12:15pm - 1:15pm
Lunch & Networking Break
1:15pm - 1:45pm
Opening Keynote- Dr. Stacie Walton & Yvonne Dotson, RN. “Endangered . . Black Women Longevity Disparities”
1:50pm - 2:10pm
Joanna Bensz
2:15pm - 2:35pm
Judy Okten-CEO and Co-Founder, Burgeon Labs. “The Longevity Ecosystem: Unlocking the Digital Patient Journey for Better Outcomes”
2:40pm - 3:00pm
Dr. Charles Brenner- Professor & Chair, City of Hope. “Use Cases for Nicotinamide Riboside in Maintenance of Resiliency in Human Aging”
3:05pm - 3:20pm
Coffee break
3:20pm - 3:40pm
Eric Morgen
3:45pm - 4:05pm
Dr. David Furman- Director, Assoc. Professor, Stanford 1,000 Immunomes, Buck Institute. “Longevity and Space: The Final Frontier”
4:10pm - 4:30pm
Dr. Adam Freund- Founder & CEO, Arda Therapeutics. " Eliminating pathogenic cells that drive chronic diseases and aging"
4:35pm - 5:05pm
Founders Panel: Challenges and Opportunities in Building a Longevity Company- Robin Mansukhani, Dr. Maddalena Adorno, Dr. Francisco LePort, Dr. Joe Rodgers
