Urolithin A (UA) One of 4 Promising Agents 2024 by Brian Kennedy of NSU

I started Urolithin A, and really can’t notice any effects.

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Which brand is this, the name, manufacturer, dosage?

I am ultra sensitive to all supplements and meds so perhaps it is just me.

You might want to try the UA made by Neurogena.

Mitopure. I don’t know why it costs twice as much as the one from Neurogena… doesnt seem to be very effective.

I tried the Neurogena brand. Maybe it’s just not for me.

Generally a well regarded company in my other groups, been on Q&As with the owner. Here’s the product: Undefined Relief with MitoCure Rx Treatments – Wizard Sciences. it’s supposed to have the full dose of Urolithin plus some other supplements which make reasonable sense to combine.

@CJZ @francesss7ca UA is a bit more like a medicine than a supplement in the sense that they managed to get a lot of patents for it. So perhaps try and see if they have a license to the patents - otherwise it would be rare for a super legit entity to also be a patent infringer.

I’ve read it may take up to 8 weeks to notice

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The same here.

I tested for one year. For periods, even 1g a day and nothing.
The gains in the studies are quite small and in some they even had better gains in the 500mg dose against 1g.

The idea is brilliant though. Also now they are trying to provide the test if you have a gut absorption, but I am afraid of the accuracy of this test.

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https://www.iherb.com/pr/super-nutrition-urolithin-a-250-mg-60-liquid-veggie-capsules/142031

Seems to be legitimate at $35 for one month.

The patents is for a use. That only really affects marketing. People can sell UA as long as they dont say what it is for.

Lost my interest after listening to Mark Tarnopolsy, MD, from the vid uploaded by John Hemming.

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Mitochondrial and Microtubule Defects in Exfoliation Glaucoma 2024
:warning: Preprint :warning:

Treatment of XFG TFs with a mitophagy inducer, Urolithin A, and a mitochondrial biogenesis inducer, NAD+ precursor, Nicotinamide Ribose, improved mitochondrial bioenergetics and reduced ROS accumulation. Our results demonstrate abnormal mitochondria in XFG TFs and suggest that mitophagy inducers may represent a potential class of therapeutics for reversing mitochondrial dysfunction in XFG patients.

Modulating Human Skeletal Muscle with Loading and Unloading 2024
:warning: PhD thesis :warning:

In the first clinical trial to administer the natural post-biotic Urolithin A during immobilization, a nutritional beverage with Urolithin A did not mitigate immobilization-induced reductions in mitochondrial content, muscle size, muscle protein synthesis, and muscle function.