That actually seems like a great weight. I would not worry about that.
@LaraPo - Yes, I agree that the Rapamune could be part of the equation. I still would follow trends, make sure your carb count is reasonable and even consider adding Metformin vs. using a lower dose. These are just a few thoughts.
If your weight is that low, I agree with @rivasp12 about checking with endocrine to r/o other issues.
My thyroid was checked and it’s good. Parathyroid as well. Ovaries seem to be normal. All bio markers are within normal range besides high LDL. Don’t get me wrong: I’m not loosing weight. My weight is the same all my adult life (+/- 5 lb). I’m mostly vegetarian and don’t consume more than 1400 cal/day. I also exercise every day, averaging 9000 steps/day. In addition Rapa mimics starvation and I’ve been on it for 12 years. With all that, it’s difficult to gain weight unless I start eating much more and move much less. I’m not used to eating much though. If I add Metformin, gaining weight would become even harder.
@LaraPo - I really think you are doing a great job! I forgot about the Rapa use for transplant. Weight is tricky with you because multiple factors that can affect your transplant balance. Higher protein can be a little rough on kidneys. Metformin can be compounded in a transdermal form, but with your long use of Rapa, weight not high, insulin controlled and only minimal changes of A1C and LDL, I am not sure big moves would be worth it. Consider a calcium score test vs. CIMT. Otherwise, I think you are way ahead of most.
Compounding transdermal Metformin is a great advice! Will address it with my GP. Thanks a lot!