TIME: Rapa, SGLT2i and GLPa chosen for first Phase 3 clinical trial in aging!

[Thor1]

Holy smokes….thanks for sharing. That is an impressive regime.

[relaxedmeatball]

@Davin8r

People who take GLPs need to eat enough protein AND follow even a basic resistance training program. If you lost too much weight too fast, then your dose was probably too high and/or you ramped it up too fast.

YES, exactly. Pharma companies are desperately trying to make “the next big thing” and make fancy molecules to preserve muscle while on GLP-1s. But all you really need is to hit the gym.

@DavidCary

Humans are fallible. Annoyingly so. Even you admit that your medical issue is/was somewhat affected by stress which some people would dismiss as your own fault - lack of self awareness or discipline. All in your head or something to that effect.

Agreed. Physicians see a reality which many of the rest of us do not. For example, compliance with actually taking medications is a huge issue. I read that when you prescribe statins or blood pressure medications, only ~50% of people are going to actually take them. You invite people to colonoscopies, and less than 30% book an appointment.

So now there’s a “magic”, infrequent, injection which is very low effort and delivers massive, obvious results. No wonder the general public are all over it.

[Cole]

@CronosTempi

I am not doubting you are a practicing published doctor. I am not. I can say though you are a highly unusual doctor, perhaps singular and unique.

To be honest, I feel the same way looking at this medication list. It’s a lot of fringe supplements, including peptides—it’s hard to imagine a doctor actually taking all of these.

[Deane]

I have seen reports from several people that they were on a very low dose, something like 1 mg I think. No one seems to know why this happens to some people but not to most.