You’re probably seen the recent thread in DNP or maybe you were active there - but I would offer a couple thoughts on that one. It’s notable that I do not see bodybuilders using DNP these days. My coach trains pros and was himself mentored by one guy who placed 2nd in the Olympia and another guy who has trained multiple Olympia winners (no joke!), and they do not go near DNP. These are guys who will use multiple compounds in high doses at once, but they do not go near DNP anymore. Now, you may know that you can get it in tablets from China, but it’s pretty high risk. If I were to use it, I would send 3 tablets to Janoshik for variance testing, or I might use a precision balance to measure out powder myself.
Safer alternatives would be tesamorelin, which you can get for about $1/mg from China, or even oxandrolone. But I would start with tesamorelin. That combined with tirzepatide or retatrutide should reduce visceral fat significantly in a deficit.
All that cagrilintide did was make me tired, but most will pair it with semaglutide and I didn’t do that. I was looking for more appetite suppression than I get from retatrutide, and I didn’t want to add in tirzepatide at the time. The dosage was just what a lot of people on forums tended to start with. Some start at half that, but I have a high tolerance for most drugs.
If you do use DNP, you need to know if you have the crystalline form, and you must be aware of the long half life because it will build.
@Mantheunknown editing this to ask if you have looked at BAM-15 as another alternative to DNP? It’s a bit expensive, but it is safer and gaining in popularity.
You may want to increase your telmisartan dose of you’re running higher anabolics. I doubt 20mg is enough to prevent cardiac remodeling. I have to go down to 40mg when my cardio is on point, but I can take 80mg without blood pressure getting too low when it’s just OK. I don’t seem very susceptible to it’s effects though. 80mg takes me from 120/80 to 110/70 normally, and 100/60, which is too low for me, when I’m psychotic on the cardio.
I have tesamorelin. I have not used it yet. Will do it after my current ‘experiments’ conclude, and I have testing results. I was planning on adding cagrilintide to my tirzepatide, am currently on 15 mg. I take160 mg of telmisartan. My potassium levels are ok. I too have a fairly high tolerance for these excursions!. Cheers
I feel heathier than I have in many years, but it has been a slow, steady progression since 2021 when things went downhill for me. Sleep is better than ever, HR is nice and low at night, HRV is improving, mood is pretty good, so generally being in more of a parasympathetic state contributes to feeling healthy. I’ve gotten my fitness to a solid level, that also helps.
What is interesting is that changes in my training (less intensity), adding cold plunge, working on mitochondrial function with peptides and research chemicals, and reducing oxidative stress via some less-popular ways, have moved the needle more than any pharmaceutical medications that I’ve tried.
Am I aging slower? I don’t know… I guess low cholesterol, low inflammation, good insulin sensitivity, and good body composition are at least markers of lower disease risk, yet I’ve been deliberately pushing mTOR up so I’m sure that is aging me a little faster than ideal and increases my cancer risk. HGH is tricky because I feel so much better on it yet maybe the IGF-1 isn’t good.
I guess the broader question, the one we all wrestle with, is how to find the balance between feeling good / performance and longevity. For me, I take a multi-factorial view that takes my personal temperament and belief system into account, which means my objective isn’t simply to live as long as possible. I don’t fear death - I think I will be much happier in the afterlife and look forward to it - but I would like to be around long enough in good enough health to help my kids and grandkids and as many people as I can along the way. And I do feel better when I look better, so I acknowledge that, accept it, and work towards it regardless of whether it may be a character flaw that might reduce my lifespan.
No I do not. I have a precision balance for measuring out. I intend to be on it for a very short duration. Just long enough to remove a pound of fat. Will use DEXA to monitor. No question of allowing it to build up. Will PM you. Thank you. Cheers
More recently, cold plunge, SLU, NAD+ injections, 5 amino 1mq, SS-31, injectable glutathione, injectable l-carnitine, ,injectable ITPP, and C60 have been the feel good mix.
Wow. That’s way down town.
The machine that measures your insulin is obviously newer/more accurate than the machine that analyses mine…it has 2 IU as the lower limit of detection. So mine just come back as “under 2 IU”.
Fasting or post-prandial…still under 2.
My GP nearly fell off his chair.
I take metformin and Sirolimus that might have some effect, but not much else. I have a sister who is very similar to me so it might be a genetic thing.
I find I need to eat at regular times or I quickly get weak and then a headache.
It kind of sucks to know I probably haven’t been getting the benefits of Telmisartan beyond blood pressure by only taking it at 40mg for over a decade. Whenever I went higher, I wouldn’t be comfortable with my blood potassium levels being north of 5
One step at a time. Don’t like to mix too many items, esp the injections. My HbA1c has improved quite a bit from 11.9 two years ago to ~6.5 to 7.2 thus far. 4 readings below 7.0 is my next goal. My BMI is at 24.5 need to drop some more. Weight / visceral fat reduction to improve insulin sensitivity is my current focus. These activities have become a full time job! Cheers
I’m having dental implants installed, so I am always interested in dental bone health and the impact of various medications. I have just initiated telmisartan 20mg/day, so this is interesting, but big caveat, this is in RATS.
Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease