Alex - thats a good summary. What AI system did you use to generate it?
To add another datapoint to the thread my 48hr drug level with 2mg Dr. Reddy Rapa was undetectable at <2ng/mL. I donât augment with anything aside from take it with a fatty meal (olive oil). Will try 4mg for my next test but if I take 4mg weekly my glucose and ApoB go
up. On 2mg ApoB was 67, glucose 69, and insulin 1.6. Canât dose 3mg because the Dr. Reddy tabs donât split very well.
Iâm guessing the new Deep Research from OpenAI
What is the recommended sirolimus test in the US? The one from Ulta is kind of expensive ($123) to do weekly, which I would like to do for a few weeks.
Why mess around with Siroboon or Dr. Reddys when you can use Zydus or Rapacan? Avoid problematic brands.
If thatâs addressed to me, Iâm taking rapamune. My goal with testing serum sirolimus levels is to find the dose with piperine thatâs equivalent to 6mg standalone. Ultimately to reduce the cost/hassle of sourcing higher quality rapamycin.
I thought Dr. Reddy was a reasonable generic Rapa? It was what Dr. Green recommended to all his patients.
Dr. Reddyâs is compounded, correct? I believe the enteric-coated tablets are the best.
(EDIT: Dr. Reddyâs appears to be enteric-coated.)
Nah not compounded to my knowledge. There is a press release from 2014 saying it is an FDA approved generic equivalent to Rapamune. Generics, to my knowledge, undergo quality control and potency testing.
No,not compounded. Any of the generics are going to have some sort of barrier or technology for getting the rapamycin through the stomach to the small intestine. Dr. Reddyâs is a generic manufactured in India but sold as a generic in the USA, so its fine (as a general product).
My pharmacy was giving me siriolimus from Dr. Reddy⌠got it for a yearâŚhard outter shell like an M&M and beige, triangle shaped. Then they switched to Zydus round greenish tan color.
I liked it the best.