Side effects from even 1mg Rapamycin?

I am using Pfizer’s Rapamune 1mg, it has minimal side effects and I feel good. Contrary to popular belief, rapamycin is a very effective drug even at low doses.

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I also believe in low doses of Rapa. 1 mg doesn’t give me any side effects and works very well.

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@LaraPo , just to be clear, for people new here, you’re taking 1mg once per day (is that correct), and you’re taking it as an organ transplant patient, not specifically longevity, correct?

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Yes, it’s correct. It’s prescribed not for longevity, but as a transplant medication. Rapamycin is an amazing multipurpose drug.

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I’m pretty small, 5ft3”
I dose with 5mg and don’t feel like I have any side effects except mouth ulcers (and these sometimes seem to appear within hours of taking rapamycin)

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Hi I have a friend who just started a low dose she intends to stay on so came here to try to find a study someone posted that said ongoing low doses can have the opposite effect intended but seems you and others are doing well with that dosage? I think she’s just taking .25mg 2 or 3 times a week as very sensitive to drugs.

I feel down the next morning and sometimes even longer after taking even 0,5 mg Everolimus, once in 3 days. I take it with a bit of grapefruit juice or cbd oil, as i’ve read that amplifies the effect. (It really does). Also, i know it lowers serotonine for a few days after, and for me is noticeable, though i weight 73 kg (not so small). Plus, when focusing on screen, have headaches from high blood pressure.

I had side effects on my first doses.

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