I am considering Retatrutide. Does anyone have any more recent recommendations for sourcing and personal experience with the product? Also what kinds of doses are you using? I have been on Semaglutide so I’m already adjusted to larger doses of Semaglutide, and not needing to start with the baby doses. I am lean, non diabetic but looking to maintain good metabloic health.
PGB has RT 10 or 24mg options in stock now.
How are you able to maintain your weight with large doses? I’d love to hear any tips you might have because I’d love to take larger doses more regularly for greater potential health/brain benefits. I barely took it last year but I’m committing to be more regular going forward.
Do you simply ‘eat through it’? Or?
I take aprox 1mg and only notice slightly tamped down food noise, in a good way. I still want to eat.
If you need help with PGB, let m know.
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Thanks Beth! I do a lot of exercise and this keeps my appetite intact, but Sema does not allow it to get too high. I’m going on a cruise next week and that will probably lead to more than sufficient calories.
I’m wondering what PGB stands for?
I will look into that company.
FYI, with retatrutide, you will probably feel much less appetite surpression than with semaglutide. That bothers some people. Make sure you’re not one of those people!
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Thanks for sharing this point. I do like having some appetite suppression. I also like that Sema reduces my taste for alcohol to zero, and the sleep benefits that have resulted from becoming a tee totaler.
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Only the total weightloss matters and reta is king in that regard.
You would think so. But Some people like to have a certain level of appetite suppression. I’ve seen many tales of people trying to switch to retatrutide from tirzepatide or semaglutide and end up dropping retatrutide.
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Given all the potential long tail risks with injectables aside from purity (sterility, endotoxins, etc), I’ve been really curious about oral agents like orforglipron. Should be coming out commercially this year, has been through all 3 phases of clinical trials, and now starting to show up in gray market sources.
With oral agents, you really only have to care about purity and that’s it. No risk setting off an endotoxin crisis or giving yourself sepsis from an especially nasty bacteria that made it into your vial.
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I don’t think the testing labs gray people can test for purity for pills anyway, just mass. Don’t forget about possible liver issues for pills, which can be a concern for oral medication.
I haven’t seen a GLP1 fail an endotoxin test so far, based on fda limits. I’ve looked at dozens of these over the past 12 months.
You should definitely filter your peptides with a 0.22um filter to take out all bacteria from your solution.
Fwiw the orforglipron I’ve seen is capsules or powder (or powder put into a solution) so testing is pretty straightforward.