Or sensitive.to the sulphites. All wine has them unless the label specifically says not.
Today I read fucoidan helpful too: Fucoidan, a polysaccharide found in brown seaweed, has shown promise in reducing Lp(a) levels. Studies have demonstrated that fucoidan can increase lipoprotein lipase (LPL) activity, which is involved in breaking down Lp(a). Additionally, fucoidan may inhibit the uptake of oxidized low-density lipoprotein (ox-LDL) by macrophages, which can help prevent the formation of foam cells, a characteristic of atherosclerosis.
Here’s a more detailed look at the potential effects of fucoidan on Lp(a):
Increased LPL activity:
Fucoidan has been shown to increase LPL activity, an enzyme that hydrolyzes triglycerides in Lp(a). This increased activity can lead to a reduction in Lp(a) levels in the bloodstream.
Inhibition of ox-LDL uptake:
Macrophages play a role in atherosclerosis by taking up ox-LDL, a modified form of LDL that contributes to plaque formation. Fucoidan has been shown to inhibit the uptake of ox-LDL by macrophages, potentially reducing the formation of foam cells and slowing down the progression of atherosclerosis.
Other potential mechanisms:
Fucoidan may also exert its effects on Lp(a) by modulating the expression of genes involved in lipid metabolism, such as SR-B1, CD36, and PPARS, which can promote lipid uptake and metabolism. Additionally, fucoidan can increase cholesterol efflux from THP-1 macrophages, a process that helps remove excess cholesterol from cells.
In summary, fucoidan’s potential to reduce Lp(a) levels stems from its ability to enhance LPL activity, inhibit ox-LDL uptake by macrophages, and modulate gene expression involved in lipid metabolism, all of which contribute to a healthier cardiovascular system.
Fucoidan is another HDAC inhibitor.
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I use it because it also inhibits PAK13/Akt/Mtor which I need re I have an acoustic neuroma. Prof Maruto recommended it (he has studied neurofibratosis for many years) I do not have NF2 but have a sporadic AN. Same pathway tho
Did you lose some hearing because of it? Did an MRI scan show it?