“Absorbed in the small intestine…”. Yes you remember correctly. And that is a very good question. I think that bioavailability is likely better if you can get it past the stomach acid to the small intestine. However that being said, when I got the powder from Alibaba (my first experience with Rapamycin as a newbie), I cut it with granulated sugar and put it in regular gelatin capsules to take 6mg per week. That’s assuming the powder I got was relatively pure.
I got an oral ulcer in the first week. And my swollen prostate that had been getting me up to pee several times a night shrunk so that I got a good stream and slept well. The ulcer resolved in about 2 weeks. I am very satisfied that I was getting the effects of Rapamycin. Unfortunately, since I live in a situation in Japan now that does not allow me to pull blood and have assays run, I have no quantitative results to back that up.
After a few months of taking the Rapamycin from Alibaba, I joined this group and so I decided that getting Rapamycin tablets from Indian sources (Kachela Medical) was more of a sure bet as far as purity and efficacy.
My opinion, from these personal experiences and from my reading, is that some of the Rapamycin makes it past the stomach acid, but I don’t know how much, especially in a horse. The Rapamycin powder in the link I sent is soo…… dirt cheap (1000Rupies/kg=$11.50/kg + whatever the shipping is). Jeez!, can that even be right? I think you could afford to give whatever the calculated dosage comes out to be. And then have blood levels run. The concern is underdosing, so you’ll do no harm. When you have blood level results in hand, then you can adjust the dose to account for how much is lost in passing through the stomach.
By the way, Merry Christmas and a HAPPY New Year!!
