Rapamycin and red light/NIR therapy

On another note, I’m aware of the very select few trials that suggest NIR (and red light) could increase collagen synthesis, albeit it has been a while since I looked at them. Out of the top of my head these were small trials, and I remember at least one of these trials was sponsored by a company that manufactures light panels and lamps.

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Love my platinum 900s been using for 18 months. My skin and hair are phenomenal,
Also helping my bad knee where I have osteartrits lots of metal plates and screws from my tibia plateau repair.

Do you happen to have any ‘before-after’-images?
In line with what the other member (Basil) also commented: I have not seen any changes in skin/hair after using a panel 10 minutes per day for 7+ months. I’ve also not seen changes in some localised inflammatory issues.

Having said that: I did not buy the panel in the hope it would affect my skin quality. Since as far as I’m aware there are only two very small trials that claim NIR/RED-light can improve skin/collagen quality. One of these two studies was sponsored by a manufacturer of these lamps. I haven’t looked into the other study for a while but it may very well be sponsored also. No convincing research with that regard imho and as I discussed above: in fact plenty of research points out (N)IR upregulates different MMP’s.
On the other hand there are many studies pointing out a wide range of other potential health benefits of NIR, among others when it comes to secretion of mitochondrial melatonin. Which was the reason I bought a panel.

Sorry I don’t have the best photos, I will still try to send you some when I can’t figure out how to attach them from my iPad.

I have been using the platinum 900x2 panels 6 feet x 1 foot roughly 3 x a week 20 minutes, I turn several different ways. Been doing it almost 1 1/2 years.

My dark Spots definitely diminished, my skin does not seem to burn in the FL sun with no sunscreen. I don’t use moisturizer anywhere but my face. Eyebrows definitely growing in although they are kind of think and dark so it might not be a good thing.

Added bonus my post menopause dryness issues seem improved!

Wrinkles not much improvement, eye bags not much improvement. Definitely hasn’t helped with fat loss or sleep. My knee which has all kinds of metal in it is working really well but I am also doing PT and getting Synv- visc injections.so who knows if they are all working together.

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Thanks so much for your post, Patty. I’m glad to hear it is working so well for you!
I’m using the panel 10 minutes per day, also from different sides. My experience is a bit difference than yours it seems: the past months I developed some light freckles/small spots of hypopigmentation on my nose/face of which I have wondered if they may be the result of the panel. As I haven’t been in the sun and didn’t have freckles priorly.

The study posted by Rapadmin above has before and after pics.

Reposting.

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Another thought

Is that Infra Red raditation creates serotonin which is then converted in the mitochondria to melatonin which is then used in the mitochondria to hold back oxidative stress.

This is the study I also referred to in my previous post. It had 136 study subject, of which 23 controls. And it was a sponsored study: “This study was fully funded by JK-Holding GmbH, Windhagen, Germany. All materials, light sources, and evaluation equipment were provided by the sponsor.” JK-Holding sells these lights.
Personally I’d like to see more studies that are not sponsored, concerning the claims in the study that ELT/RLT exposure would increase collagen density. Certainly in light of the many studies that suggest (N)IR upregulates different MMP’s in the skin.

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Recently I found that when I combined Rapamycin and red light, I got more severe acne and rash. But when I used red light alone, I didn’t get any acne nor rash.

Here are some combinations I have tried on myself (N=1)

  • Rapamycin alone: Mild acne/rash
  • Red light alone: No acne/rash
  • Red light before Rapamycin: Mild acne/rash, same as Rapamycin alone
  • Red light for 3 days after Rapamycin: Severe acne/rash
  • Red light for 7 days after Rapamycin: Very severe acne/rash
  • Hot bath after Rapamycin: Mild acne/rash, same as Rapamycin alone

I guess there might be some interactions between rapamycin and red light.

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I have been using Retin A for +10 years at night, Joovv red light for 10 min every morning and Rapamycin 6mg every week for 9 weeks with Olive oil and metformin and have not experienced any rash despite having sensitive skin.

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What educated persons use anecdotal evidence to prove anything? Relational vs causation.

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A lot of anecdotal information… N=1 to see if there is any other user correlation.

Not proof… but a starting point.

When I let Matt Kaeberlein know my dysphagia went away after 6 months of rapamycin use - it intrigued him. The potential of rapamycin is still very unknown in people due to lack of general use. If nerve cells regenerated… why shouldn’t neurological issues repair.

From his perspective, swallowing issues are definitely a functional decline seen in the elderly. Rapamycin very well could repair this issue. He seemed to think a great starting point and
it could be worth a human clinical trial down the road.



Finally have some photos of the difference red light has done. First photo a year before starting red light therapy, second after 2 years of therapy. Platinum LEDs probably average 4 times a week.( no the Diamond is nit mine🙄) my friend was letting me try is on…

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Looks good. I am going to start using my long purchased red light panel (660 nm). What frequency are your red lights? 660? 850?

Did the red light improve the diamond?

Unfortunately the diamond went back to my friend…

The platinum lights have five frequencies 630, 660, 810, 830 and 850 some are infrared. They have also done amazing things for my eyebrows. They have done nothing for sleep or weight loss unfortunately…

I have two panels so 12 inches across by 6 feet high.

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Thank you. My panel is pure 660, 12 x 12. Will need to buy more, if I want it to be floor length.

Who is the manufacture of the panels?

Product information?

Platinum LED
Biomax 900 two panels. The hand nicely on the closet door. They have now added a bit of blue lights to these panels.

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In a 2012 study, China-based researchers assessed the effect of red light therapy on the sleep quality and performance endurance of 20 female basketball players. Half the players received 30 minutes of full-body irradiation from a red-light therapy machine that looks like a tanning bed. The researchers found this group had greater improvement in sleep and serum melatonin levels than the placebo group, which didn’t receive red light therapy.

Given the limited research, “this is one of those situations where there’s a sleep ‘hack,’ but there’s no evidence behind it really,” said Joshua Tal, a New York City-based psychologist specializing in sleep problems. “I don’t see the benefit.”

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https://www.researchgate.net/publication/373466102_Optical_stimulation_of_mitochondria_reduces_blood_glucose_levels

Here we show, with a glucose tolerance test, that red light exposure in normal subjects significantly reduces blood sugar levels. A 15 min exposure to 670 nm light, reduced the degree of blood glucose elevation following glucose intake by 27.7%, over 2 h. Maximum glucose spiking was reduced by 5.1%. Decreased blood glucose correlated with increased exhaled end-tidal CO 2 partial pressure at 1 h, indicating the mechanism includes an increased oxidation rate. Consequently, 670 nm light exposure can be used to reduce blood glucose spikes following meals.

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