Rapamycin and increase in blood glucose?

[brandy111]

There is some additional discussion regarding this topic in this thread:

Rapamycin induced insulin resistance and drop in testosterone

A physician colleague of mine reported his recent lab test results after taking Sirolimus for 9 months, at a dosage of 12 mg every two weeks (0.2 mg/kg). Of note, there were no other changes to his medications, diet, supplements, or exercise regimen during this time period. His labs demonstrated a significant increase in insulin resistance (HOMA-IR doubled from 0.9 to 1.9 ; fasting insulin doubled from 4 to 8). Notably his fasting glucose only went from 90 to 92, and HbA1C went from 5.2 to 5.3, showing that these two blood glucose metrics are not sensitive enough to detect early signs of insulin resistance. He also experienced a 50% reduction in his free testosterone level, dropping from 14 ng/dl to 7 ng/dl. I recall a previous forum post in which someone reported a similar significan…

[LaraPo]

Is he planning to reduce the dose?

[sunshine4]

Its doing something to my fasting glucose as well.

I’m taking 25 jardiance and 50 acarbose for life extension, with rapamycin, and my fasting glucose was still a bit higher than last reading

[sunshine4]

As an addendum to this, sorry for giving out falty information. I should have brought up, in addition to getting rapamycin, jardiance, and acarbose from my Indian dealer, I have started on heavy duty statins after listening to Stanfield/Attia’s takes on LDL. I’ve just read that statin use can also play a integral part in raising fasting glucose.

Since taking all these substances my blood sugar has raised a couple points. Hopefully the blood sugar goes down over time. I’ve also wanted to take a different statin that seems to have a lighter affect on glucose

[Bicep]

I’m pretty sure IV vitamin C causes the machine to register high glucose, but this is a false reading. It’s reading the vitamin C. IV C always does this. My daughter gets 75 grams twice a week for cancer.