Rapalog companies?

Krister, review the Nir Barzilai interview in detail.

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@anon16510610 yes, that is one interesting trial. Lets create a thread on community driven rapamycin trials.

@Joseph I listened to that podcast some years ago when I deep dived in the metformin area. What in that episode did you want to highlight?

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This is rather interesting… navitor has out-licenced a compound that I think is an motor inhibitor, for use in depression…

https://www.fiercebiotech.com/biotech/supernus-links-depression-drug-fast-responses-small-trial

Yes, I saw David Sabatini reposted about that on X. Very interesting but it seem like its a mTORC1 activator?

Supernus Pharmaceuticals has linked its mTORC1 activator to rapid improvements in adults with major depressive disorder (MDD) in a small trial

Here is one presentation that I also found about the trial

https://ir.supernus.com/static-files/ab65cf23-b874-4b16-819b-13eb197962e7

And one video where they talk a little bit about the trial

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Good info - thanks. I assumed it was an mTOR inhibitor as that was, I believe, the focus on Navitor, but perhaps they are more broadly looking at all types of mTOR related molecules.

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