Just received some ACD856 and I’ve taken my first dose. I will be trialling this short term to see how it goes.
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@adssx I’ve been planning to make P7C3-A20, so if other people are interested I could have some in ~3-4 weeks. In-house confirmation with LC-MS and 3rd-party quantitation w/ qNMR.
P7C3-A20 has also been tested in primates and shown to promote survival of nascent hippocampal neurons without affecting proliferation. I’d speculate that for long-term function this mechanism is safer than proliferative mechanisms (e.g NSI-189) that may accelerate neural stem cell exhaustion.
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Obesity and high blood pressure may directly cause dementia
The findings highlight weight and blood pressure control as potentially powerful tools for preventing dementia before symptoms appear.
A new genetic study suggests that obesity and high blood pressure may play a direct role in causing dementia, not just increasing the risk. By analyzing data from large populations in Denmark and the U.K., researchers found strong evidence that higher body weight can damage brain health over time, especially when it leads to elevated blood pressure. Much of the dementia risk appeared to be tied to vascular damage in the brain, which affects blood flow and cognitive function.