It does significantly reduce rates of prostate cancer and prostate cancer mortality but there is only a trend towards a lower acm. Sadly we don’t have any comparative data for 17a-estradiols effect on human longevity.
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Androgenetic alopecia (AGA) is the most frequent form of alopecia in men and women. It is characterized by progressive hair loss, usually in a pattern distribution. The onset may be at any age following puberty and the frequency increases with age. By the age of 70 or beyond, 80% of Caucasian men and up to 40% of women have signs of AGA. Today, in our societies, hair is an important feature of image; strong and dense hair is associated with youth, beauty, healthiness and success.
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The cause and effect here looks all backwwards at best.
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Who here has noticed better skin quality since starting fin?
Alongside hair loss prevention younger and smoother skin is always a plus, as dht ages skin, even a very low dose lowers skin serum dht by a lot as shown by this study previously reported earlier:
Background: Data suggest that androgenetic alopecia is a process dependent on dihydrotestosterone (DHT) and type 2 5alpha-reductase. Finasteride is a type 2 5alpha-reductase inhibitor that has been shown to slow further hair loss and improve hair growth in men with androgenetic alopecia.
Objective: We attempted to determine the effect of finasteride on scalp skin and serum androgens.
Methods: Men with androgenetic alopecia (N = 249) underwent scalp biopsies before and after receiving 0.01, 0.05, 0.2, 1, or 5 mg daily of finasteride or placebo for 42 days.
Results: Scalp skin DHT levels declined significantly by 13.0% with placebo and by 14.9%, 61.6%, 56. 5%, 64.1%, and 69.4% with 0.01, 0.05, 0.2, 1, and 5 mg doses of finasteride, respectively. Serum DHT levels declined significantly (P <.001) by 49.5%, 68.6%, 71.4%, and 72.2% in the 0.05, 0.2, 1, and 5 mg finasteride treatment groups, respectively.
Conclusion: In this study, doses of finasteride as low as 0.2 mg per day maximally decreased both scalp skin and serum DHT levels. These data support the rationale used to conduct clinical trials in men with male pattern hair loss at doses of finasteride between 0.2 and 5 mg.
So even 0.5mg 3x weekly may do the job, which is currently what I started. The reason i dose 3x weekly is skin dht stays reduced for quite a while even though finasterides half life is only a few hours
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Finasteride is only a very weak 5ar type 1 inhibitor so you shouldn’t expect it to improve your skin beyond what the 10-15% extra estradiol will do.
Anecdotally I can confirm that as my skin still gets oily quickly.
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