New Idea for dosing Rapa

Its a dosing strategy that is somewhat similar to what this guy who was trying very high dosing levels used: One User Trying Very High Doses of Rapamycin, and Negative Adverse Events / Results

We really have very little data on the optimal dosing right now - all we know really is that the Mannick Paper was successful with a dosing schedule at 1 week for Everolimus (RAD001): mTOR inhibition improves immune function in the elderly - PubMed

Anything other than this is just speculation without much data behind it… it could work better, or not. I’m not even sure how we’d test to know if its better. yes - you are right, it will increase the AUC. But so would just higher single doses.

Unfortunately, right now its really hard to tell.

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