Dr. Brad Stanfield is releasing a powder version soon of his multivitamin and adding extra taurine (bringing the total to 2.5g combined with the magnesium taurine), collagen peptides, creatine, and psyllium husk, among other things.
Looks pretty good. I would have liked to have seen higher amounts of Lutein and lycopene, along with an addition of zeaxanthin, but still pretty good.
Funding Rapamycin Clinical Trials, one berry powder sale at a time.
There is a definitive lack of a good eye-health supplement (12mg astaxanthin, 10mg lutein, 2-4mg zeaxanthin) on the market right now.
Iāve been using this. Kinda pricey, but I like that it has so much in one cap, including high dose Vit K2 MK7
FWIW, Iāve read somewhere that astaxanthin displaces lutein and so these two should not be taken together. Unfortunately I canāt remember where I read that, so I donāt know how reliable that is, might be nothing. Astaxanthin stays in the blood for quite a while, so it would be hard to take them far apart enough to take both daily, so this whole thing might be a wild goose chase. Lutein is certainly taken up preferentially by the macula tissue. And astaxanthin also penetrates the macula (in studies of astaxanthin). If you take lutein, zeaxanthin and meso-zeaxanthin together, all three show up in the macula and the brain. What happens if you concurrently add astaxanthin, I donāt know.
There may also be a dosage issue in that perhaps there is some interference with high doses of one or the other, or maybe some tissues get saturated with a high dose so if one of these carotenoids is taken by a tissue in some preference to another, at a high dose might saturate leaving no room for the uptake of the other. No idea, pure speculation.
Anyhow, I take all of them, although I make a feeble attempt at separating the intake of astaxanthin from the others. Lutein, zeaxanthin and meso-zeaxanthin with breakfast, astaxanthin just before bed. Might be nonsense - I really should look into this at some point.
Further to my post above, hereās a study:
Effects of Lutein and Astaxanthin Intake on the Improvement of Cognitive Functions among Healthy Adults: A Systematic Review of Randomized Controlled Trials
Quote:
āOnly studies where the intake of carotenoids was oral were included in the review. Participants also had to have taken only one type of carotenoid, however, the simultaneous intake of two or more types of carotenoids was allowed if the combined carotenoids were of similar function and biodistribution (e.g., lutein and zeaxanthin) [23]. Studies were only admitted to the SR if two or more groups of carotenoids were administered and an orally taken placebo was included in the treatment design.ā
Here we have a study implying that combining astaxanthin, lutein and zeaxanthin is possible insofar as this combination has a biological impact, but it does not tease out the impact of the individual components, or whether one might have displaced the other, or otherwise was additive or subtractive:
Effects of Astaxanthin, Lutein, and Zeaxanthin on EyeāHand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial
Hereās an abstract in zebrafish, and it looks like they tested astaxanthin, lutein and zeaxanthin, but unfortunately separately. However, what was interesting, was that lutein was by far the most protective, with zeaxanthin next, and astaxanthin last:
Comparison of the protective effects of astaxanthin, lutein, and zeaxanthin from AMD-related vision loss in zebrafish
https://iovs.arvojournals.org/article.aspx?articleid=2796505
āAstaxanthin protected the retina from the A2E damage over this same period. In fact, the visual acuity increased nearly 10% compared to baseline (p=0.036 n=10). Lutein had an even larger effect, not only protecting from vision loss but also seeing an improvement of visual acuity of 33% (p=0.00079 n=7). Luteinās effect was significantly larger than that of astaxanthin. Zeaxanthin also protected from the visual acuity loss and was in between both astaxanthin and lutein with a 16% improvement (p=0.0055 n=7). Two weeks after A2E treatment, fish retinas a reduced cell density, whereas lutein, the strongest performing carotenoid protected the retinal cells.ā
People can say what they want about BJ but this looks like a very good supplement that combines several important things all into one.
To follow up here, I have been using this powder supplement since it was first released so I have gone through 3 tubs now. One scoop in my usual morning breakfast smoothie and it combines lots of different supplements I was taking anyway all into one. I think itās quite a good product. I think he should increase the amounts of lutein & lycopene while adding zeaxanthin, but beggars canāt be choosers. I put kale in my smoothie to get the lutein/zeaxanthin and eat watermelon to get the lycopene instead.
I believe all three are worth taking. A significant amount of lutein/zeaxanthin can be had by grabbing a handful of raw kale every day but astaxanthin needs to be supplemented (can take away from the kale if one is really concerned with separating them) to get the beneficial amounts because letās face it, no amount of salmon is going to get us to 6mg+.
I agree, I love my two BP supplementsā¦ lots of stuff in a total of 3 pills
I checked out Bradās powder. So many people take collagen anyway, it seems like itās a slam dunk just to knock out so many things with it. If I consumed beef, Iād get it!
MicroVitamin isnāt too expensive in comparison to the individual ingredients if you get a subscription. Bradās Sleep supplement is a total cash grab though.
Totally agree. I do the subscription for the MV+ powder to knock the price down. The sleep supplement seems unnecessarily expensive though. Would be much cheaper to take each of the three ingredients separately (each isnāt even dosed that high to begin with).
