Metformin decelerates aging clock in male monkeys

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Elsevier is Dutch-owned.

You must be thinking of a different paper. The senior author is Guang-Hui Liu.

Was referring to the original post’s referenced paper - Metformin decelerates aging clock in male monkeys

https://www.cell.com/cell/abstract/S0092-8674(24)00914-0

Below are the affiliations and notes.

1 Key Laboratory of Organ Regeneration and Reconstruction, State Key Laboratory of Membrane Biology, State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China

2 China National Center for Bioinformation, Beijing, China

3 Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China

4 Institute for Stem Cell and Regeneration, CAS, Beijing 100101, China

5 Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China

6 National Clinical Research Center for Geriatric Disorders, Aging Translational Medicine Center, International Center for Aging and Cancer, Xuanwu Hospital Capital Medical University, Beijing 100053, China

7 State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

8 College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

9 Sino-Danish College, University of Chinese Academy of Sciences, Beijing 100049, China

10 University of Chinese Academy of Sciences, Beijing 100049, China

11 Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, Guangzhou 510060, China

12 Chongqing Fifth People’s Hospital, Chongqing 400060, China

13 Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

14 International Center for Aging and Cancer, Hainan Medical University, Haikou 571199, China

15 Altos Labs San Diego Institute of Science, San Diego, CA, USA

16 Department of Neurosurgery, Xuanwu Hospital Capital Medical University, Beijing 100053, China

17 National Medical Center for Neurological Diseases, Beijing 100053, China

18 Beijing Municipal Geriatric Medical Research Center, Beijing 100053, China

19 Oujiang Laboratory, Center for Geriatric Medicine and Institute of Aging, Key Laboratory of Alzheimer’s Disease of Zhejiang Province, Zhejiang Provincial Clinical Research for Mental Disorders, The First-Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China

20 Department of Rheumatology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing 100730, China

21 Institute of Gerontology, Guangzhou Geriatric Hospital, Guangzhou Medical University, Guangzhou, China

22 Aging Biomarker Consortium (ABC), Beijing 100101, China

23 These authors contributed equally

24 Senior author

25 Lead contact

The names with number 24 (Senior Author) include Concepcion Rodriguez Esteban, Steve Horvath, and Juan Carlos Izpisua Belmonte, among others. Their names also show the number 15 - Altos Labs.

Yuanhan Yang1,10,23 ∙ Xiaoyong Lu2,3,10,23 ∙ Ning Liu7,8,23 ∙ Shuai Ma1,4,5,10,23 ∙ Hui Zhang1,10,13,23 ∙ Zhiyi Zhang7,23 ∙ Kuan Yang2,3,10 ∙ Mengmeng Jiang1,4,5 ∙ Zikai Zheng2,3,10 ∙ Yicheng Qiao7,8 ∙ Qinchao Hu1,11 ∙ Ying Huang12 ∙ Yiyuan Zhang1,4,5 ∙ Muzhao Xiong2,3,10 ∙ Lixiao Liu2,3,10 ∙ Xiaoyu Jiang1,10 ∙ Pradeep Reddy15 ∙ Xueda Dong7,9 ∙ Fanshu Xu7,8 ∙ Qiaoran Wang2,3,10 ∙ Qian Zhao6 ∙ Jinghui Lei6 ∙ Shuhui Sun13 ∙ Ying Jing6 ∙ Jingyi Li1,4,5,22 ∙ Yusheng Cai1,4,5 ∙ Yanling Fan2,3 ∙ Kaowen Yan1,4,5 ∙ Yaobin Jing1,4,5,14 ∙ Amin Haghani15 ∙ Mengen Xing19 ∙ Xuan Zhang20,24 ∙ Guodong Zhu21,24 ∙ Weihong Song19,24 ∙ Steve Horvath15,24 ∙ Concepcion Rodriguez Esteban15,24 ∙ Moshi Song1,5,10,24 ∙ Si Wang6,22,24 ∙ Guoguang Zhao16,17,18,24 ∙ Wei Li1,4,5,10,24 ∙ Juan Carlos Izpisua Belmonte15,24 ∙ Jing Qu1,4,5,10,13,22 qujing@ioz.ac.cnWeiqi Zhang2,3,4,5,10,22 zhangwq@big.ac.cnGuang-Hui Liu1,4,5,6,10,22,25

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Acknowledging that you’re just pointing out what the paper says, that just makes a nonsense out of “senior author:” there’s one senior author, or at most two co-seniors. It’s like saying all the kids in the class are the best student.

Rodriguez Esteban and the other people from Altos clearly weren’t doing the actual study, which was carried out in China; with their Altos affiliation, and Horvath and Belmonte being among them, they may have helped with the clock. The paper’s AUTHOR CONTRIBUTIONS section says “G. Zhao, W.S., S.H., C.R.E., M.S., S.W., X.Z., G. Zhu, W.L., and J.C.I.B. helped with supervision of the project,” which is an awful lot of “supervisors” and again difficult to do from San Diego.

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