Iron: an underrated factor in aging

It’s because sema and tirz reduce LDL-cholesterol by 5-10% and retatrutide by up to 20%.

Well yea that’s a much larger factor for CVD reduction along with reduced blood pressure. I’m just saying lower iron could add more to that reduction if someone had a higher iron status to begin with.

John Hemming: Bearing in mind costs,

What measurements do you think would be most useful for me to track and when? For example, I initially measured a standard iron panel, but when I retested I just tested for labile iron.

233ug/dL before down to 165ug/dl after. Ferratin, tibc in range.

The issue with this is that these are just blood test results. They’re not tissue samples. What else is good to test?

I can share my HTMA results before and after as well, but HTMA has a repeatability problem, so they are not used in consensus science. However, I believe it is conceivable that if we only consider samples from the same lab and relative, not absolute changes, then there could be some value that can’t be captured from any other means?

Please also feel free to mention more expensive testing as well, just to consider.
In addition, I’m in Hong Kong. If anyone knows anything about pairing with a university to get access to testing equipment, please let me know.
If anyone knows anything about testing metal excretion in urine too, please let me know as well.

While I value studies and papers, I’d like to see more people sharing their experiences with lowering iron. Experimentation is the backbone of science. Get hands-on. Even if it’s only measurement at first, starting with that free iron blood test.

Ferritin is a useful figure. Just because a lab says it is in range does not mean there is not an issue. One problem with ferritin is that if you are inflamed ferritin will be higher. Micrograms per deciliter sounds unusual units.

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