Is itt possible that in this case (or in the case of autoimmune disease prevention) that Rapamycin is simply doing its approved indicative effect: reducing immune response? And this is why it is helping people who’s immune system is attacking their own bodies? And this is also why there may be a dose response for you? If this is the case, rapamycin wont “cure” anything but will need to be taken forever to correct this “symptom”. (Still could be amazing for you)
Or is there evidence that raamycin actually changes the autoimmune response and “cures” it? That would be amazing.I have a daughter with (fairly recent) TiD and id love to find a way back for her.
I know keto/carnivore isn’t popular on this forum, but many of the people who come to it have been very sick — many with autoimmune diseases — and whatever aspect of this diet (elimination diet, nervous system quelling) seems to work for many of them (not a clinical research trial). And there is some ancillary evidence that if youve been on the diet for some time that you can ease your way off it without losing the effects. There is some speculation that all this diet really does is get you metabolically heathy but not much else. Not suggesting anyone try this. Also i have vitiligo (a minor autoimmune) and i still have it after three-ish years of mostly low carb so it did nothing in this respect for me. (By the way: “keto/carnivore” has been mentioned as terrific for many people with crohns disease, and nervous system disorders — first medically used for epilepsy — but not sure there’s much mention outside of this in autoimmune.)
My father used to have “back stiffness”, a chronicle spine inflammation caused by autoimmune attack. I am willing to take rapamycin for the rest of my life in exchange of free movement…
Yes, I tried LDN. It didn’t seem to help much… but I’ve considered giving it another go. Never tried TA1, maybe I’ll put it on my todo list… but I didin’t see any compelling research.
There is actually evidence supporting low carbs helping many AI diseases. I’ve been doing a very strict diet called, Specific Carbohydrate Diet (SCD): How It Works & Benefits , and it does seem to help; and there is evidence to support it for crohn’s.
As far as Rapa helping with A.I. diseases because it is immunosuppressant, there is no question that immunosuppressant doses of prednisone (or other corticosteroids) help me feel 10x better. But Kaeberlein always insists that Rapa is mis-categorized, and that it doesn’t suppress the immune systerm, but it modulates it. I’m not an expert in this, so I can’t really comment here.
