If this trump administration is into deregulation why can't they make medications OTC?

Sad but true…

Trump’s efforts respond to rising popular discontent and people’s sense that the companies have been reaping unusually high profits. In recent years, at least 10 states have enacted laws intended to lower drug prices.

“As a group, these companies were significantly more profitable than your typical S&P 500 company,” said Fred Ledley, a professor of science and management at Bentley University who has reviewed the financial statements for the 21 public companies whose drugs are subject to Medicare Price Negotiations. “What we have concluded is that you can cut these drug prices without harming these companies.”

But any efforts to reduce company revenue must overcome the political might of the pharmaceutical companies, which bring to bear one of the nation’s best-funded Washington lobbying machines. The companies argue that lowering prices will stifle research and allow Chinese companies to overtake those in the United States. They blame high prices on insurance middlemen and say that the answer is not to lower U.S. prices but to raise prices in other countries so that they pay their “fair share.”

Source: Trump claimed a win on drug prices, but Big Pharma also scored (WaPo)

and

As is often the case, the Trumpian diagnosis contains a kernel of truth. Drug prices are indeed higher in America than elsewhere in the rich world. But the president’s two-point prescription upends a model that has long underpinned the highly globalised pharma industry, which could have unintended effects. It could leave Americans with fewer medicines but not cheaper ones, while in other countries drugs could be fewer and dearer. David Ricks of Eli Lilly, the world’s most valuable drugmaker, has warned that mfn pricing risks “the worst of two worlds”, importing Europe’s sluggish innovation while keeping American prices high.

America’s high drug prices have long exercised politicians on both sides of the aisle. According to a study by the rand Corporation, a think-tank, they were more than three times the average in other rich countries in 2022. As a consequence, America coughs up around 70% of global pharmaceutical profits from about half of global sales.

This is partly because of how the market is organised. The supply side is globalised. Most active ingredients are made in low-cost hubs such as India; much of the research and development goes on in America, Europe and increasingly China.

On the demand side, however, prices are set locally. In Europe and many other rich countries, drugmakers must negotiate directly with governments, which have hefty bargaining power and often link payments to cost-effectiveness. In America, by contrast, prices emerge from a decentralised and complex web of contracts connecting manufacturers to health insurers, employers and pharmacy-benefit managers (pbms), which negotiate between insurers, pharmacies and others.

Although America’s public-insurance schemes, Medicaid (for the poor and disabled) and Medicare (for the old), cover about half the population, they negotiate prices for only a few medicines. Joe Biden’s Inflation Reduction Act (ira) authorised Medicare to negotiate prices directly with manufacturers. But roll-out is slow: only ten drugs will be covered in 2026, 15 in 2028 and 20 in 2029. One pharma boss says they “take what they can get in Europe”, because returns are greater in America.

Patents help keep those American returns high. About 90% of the $490bn spent in America on prescription medicines last year went on branded (mainly patent-protected) drugs with no cheaper generic equivalents. Yet branded drugs made up only 7% of prescriptions.

Source: Donald Trump is waging war on sky-high drug prices. Can he win? (The Economist)

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Absolutely! They seek the power to control people and they seek the privileges of being a politician.

Yes, I suppose that’s the case. But, I’ve discovered if I don’t provide any insurance details my price for a drug may be cheaper than the co-pay I would have to pay with insurance paying the major part of the cost. That, of course, continues to surprise me.

And, another important point in my case and I suspect many others is that I’ve paid into insurance premiums over many years and the insurance payment benefits I’ve received so far have come nowhere near what I paid in. And, yes, I know that’s the way insurance companies make a profit.

So, when the non-insurance price is lower than the insurance price (common in my case) I always go that route.

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I think the debate which meds should be allowed OTC is similar to a debate on what weapons should be allowed for US citizens to own.

Handguns - sure
ATACMS - probably not

If Zolpidem was allowed OTC, then the number of women (and men, children) that are drugged and raped would quintuple.

ALSO, from business aspect.

Antihypertensives, statins, metformin, etc - WOULD NOT SELL. 99.99% has no interest in these.
People only buy OTC meds that they “feel” working. General public wouldn’t spend money on daily pills as a preventive for a disease which may no arise for years.

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I ordered and occasionally use prednisone and ciproflaxin. Both have been used appropriately, no need for a doctor’s supervision.

Yes, the Z drugs are dirty, and beyond two weeks are dangerous.

Dose is relevant. 3.5 mil Zolpidem now and then would not hurt you much if your sleep is improved. My own doctor takes Zolpidem regularly.

Glad you’re having success with those, but I’d consider those two drugs to be significantly dangerous and poor candidates for otc use.

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As libertarian I believe that every human being should be free to harm themselves. Zolpidem is terrible for sleep architecture, I would use Belsomra instead - orexin antagonist.
HOWEVER - the harm of zolpidem that can be inflicted on to others is real. It causes a anterograde amnesia which makes a perfect drug for kidnapping in human trafficking or rapes.
For that reason it should remain a controlled substance and every prescription should be tracked.