How can sleep fragmentation be improved, especially in cases of narcolepsy?

Im sure you know about these interventions (or at least your doctor should make you aware)
Here are some

Outside of that , maybe look into Suvorexant or dual orexin receptor agonist in general:

: TAK-861, a potent, orally available orexin receptor 2-selective agonist, produces wakefulness in monkeys and improves narcolepsy-like phenotypes in mouse models | Scientific Reports

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