https://x.com/cremieuxrecueil/status/1967021861730214230?s=19
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Very interesting.
I hadn’t considered DIY GLP-1s and their variants.
Seriously considering doing this with Retratrutide.
Seeing lots of reports on its muscle preservation and reduction of visceral fat.
Key questions
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Potential of addressing metabolic risk, e.g., diabetes or pre-diabetes more directly and with fewer downsides than Metformin?
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CREMIEUX credibility?
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DIY safety?
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Would it really work?
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Prudent?
Thoughts from medical professionals appreciated.
P.S.
I do use DIY Rapmycin
As I’ve reported across the forum, I already source Rapamycin from Science.bio and use it topically and as an additive to toothpaste.
I’d use it internally if I could get proper entice coated capsules, but haven’t found any I believe I can trust.
DIY Retratrutide seems like a definite next step in biohacking.
My only concern with retatrutide is that potential cardiovascular risk. A common side effect is increased HR, but it’s unclear if that matters in the long run.
Retatrutide doesn’t spare muscle any more (or less) than other incretin mimetics, but it does work better for weight loss for most people. Adequate protein intake and at least some amount of resistance training are essential when on any kind of weight loss regimen, and there’s really no way around that other than taking some sort of anabolic/anti-catabolic compound at the same time if a person is absolutely intent on avoiding exercise (which is a very bad idea IMO).
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This is true of all GLP1s
The Twitter post is just a statement, whether that statement is true or false is debatable, since he hasn’t provided his source/justification.