Just looking for confirmation on the Zydus, thanks.
Ah! Your Zydus pills are the same. I zoomed in closer and could just make out the “351”.
Thanks. Feeling more confident about the product. “351” probably refers to something that is not specific to the drug itself.
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My Zydus tablets have 351 stamped on them.
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Are those tablets enteric coated?
All the commercial sirolimus tablets have some sort of coating to avoid the disolution in the stomach (vs. intestine).
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If there’s one thing manufacturers would cheap out on is the enteric coating, as I think that’s a relatively expensive part of the process. At least Nootropicsdepot’s enteric coated NMN cost more than twice the amount compared to standard. I’m not saying it is now, but one thing to look out for in the future. And they had a lot of problems with their enteric coating, not meeting the required specifications, changing different manufacturers.
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How can I tell if it has enteric coating?
Thanks. It seems my Zydus is what everyone else is getting.
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I suppose you could prepare a few acid solutions which you compare different tablets and capsules, like rapamune in one, zydus in another, random supplement in another, enteric coated capsule in another, etc.
The idea of someone going through the effort to make fake zydus rapamycin pills that actually have matching imprints and packaging… it would be one of the dumbest scams of all time. The market for these are incredibly small and the real ones aren’t even that expensive.
I’m not saying this might not be a problem some day, but there really aren’t enough of us out here yet to be worth the effort and expense of making fake product to scam.
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I completely agree but I wanted to confirm after coming across the Drugs.com pill identifier, which I posted at the top of the thread.
Exactly… there are I think a few very good reasons that rapamycin is a poor target for counterfeiters (and therefore a low risk for us of getting “fake” drugs):
- Generic/Low cost drug (so minimal profit potential for counterfeiters)
- Small market (there are about 70,000 organ transplant patients in the USA per year and only some of them use rapamycin/sirolimus. The market for the longevity community is perhaps a few thousand people right now. Compare this to a drug like semaglutide (wegovy) still on-patent, and in demand potentially by about 50% of the population for weight loss and diabetes… You have to assume that anyone making a fake drug would rationally prefer to sell it at high price (i.e. non generic drug) to tens of millions of people, vs. sell a cheap drug to a few thousand people.
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Newbalance, I see your point as well as the points everyone else is making. However, I checked the website and noted the 6 mm diameter of the cetirizine hydrochloride pills in the specifications. I checked the diameter of the Zydus pills I have and they are 6 mm. Hmmm … I need to research further.
https://www.drugs.com/imprints/rdy-351-14298.html
I assume www.drugs.com (noted above) is for pills produced for the American market, but I can not find a pill identifier site for drugs produced specifically in India for the Indian market so far.
Arnab Kumar Nath is the General Manager of Zydus Trans-Immune (division of Cadila Healthcare Ltd). He has a LinkIn profile. Someone with the proper credentials may be able to ask him a few pertinent questions in a nice way. But, of course, the phrase “Fat Chance” comes to mind. LOL!
One last thought: Who has taken a rapamycin blood test while using Zydus Siromus? I think I was using Biocon at the time and the blood test I took was positive for rapamycin. It seems a blood test would be reasonable proof of Zydus not being fake.
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All my Zydus tablets also have “351” stamped on them.
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I take Zydus and have taken a blood test and it definitely has Rapamycin in it.
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FWIW
This has been discussed in other threads. You will spend more on testing than purchasing real Pfizer RAPAMUNE® (sirolimus).
Getting a prescription and purchasing at a local pharmacy will cost you much less than testing.
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I also have a doubt on my Zydus sirolimus, by google search i found this post.
No feeling, no side effect after 3 weeks in 6mg-12mg-18mg dose. Share my sirolimus
snapshot, however, glad to find out low chance of getting fake rapamycin.
FWIW
You could have a blood test preformed after you take your rapamycin. This is the least expensive way to test.
Blood testing for rapamycin for $60.00 through Marek Diagnostics.{the same LabCorp test, this is $500.00 using LabCorp directly]
A discount code was available back in March 3 2023 see;
Do not know if the discount code still works as of this posting Augest 08, 2023
I have no financial interest in Marek Diagnostics.
As sending a sample from your purchase would cost much more than your purchase. As I stated above;
“You will spend more on testing than purchasing real Pfizer RAPAMUNE® (sirolimus).”
Testing a sample would cost $1,000 or more
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I got the capsules from AllDayChemist. I’ve been getting my tretinoin and tazarotene from them for years.
I know for a fact that they are not only real but also effective because they have a night/day effect on my dog.
It’s like she was asleep for the last three years and she suddenly woke up. Her eyes are clearer, she’s much more involved and affectionate, she wants more walkies, and she is much happier and interactive. She’s a rough collie and will be 13 in October. Life expectancy for her breed is 10-12 years.
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The chance of those pills being counterfeit are very slim. Lots of other drugs that are much more expensive and widely used would a more likely target.
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