I definitely have not experienced this from Retatrutide. I swear people on Reddit read someone else’s experience and then convince themselves they have it too.
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FWIW, there is apparently evidence that GLP-1 inhibitors cause people to lose muscle mass as well as fat. It is probably a good idea to combine it with resistance training.
See this video:
[Url pasted in directly on its own line. 
]
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As of today, there’s no evidence that you lose more muscle with a GLP1-RA compared to the same weight loss with diet or bariatric surgery: Intermittent (oral) Rybelsus / Semaglutide use in healthy individuals? - #420 by adssx
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So yes, absolutely combine w/resistance training and adequate protein intake, which would be true regardless of the method of weight loss.
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@adssx would you mind copy/pasting a bit more of his post for those of us who don’t have an account on X?
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It’s 8 long tweets so not super practical. Create an X account, it’s worth it
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I’ve lost 15 pounds in 2 months with 0.25mg per week of compounded semaglutide. Few side effects. I’ll switch to Tirzepatide as soon as I can get it!
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Can’t access Twitter, but I’m guessing he wants to lose more weight? Twitter not allowing people that are not logged in to see content is just hostile, BTW.
No he doesn’t want to lose weight and that’s why he’s micro dosing.
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FWIW: N=1
I am very impressed with Tirzepatide.
I am using it to eliminate a small amount of remaining external and visceral belly fat.
After only 1 week, I noticed a decrease in appetite. After 2 weeks, I had a noticeable decrease in appetite, and when I am hungry, I am satiated quickly. I rarely clean my plate.
My goal is to maintain a BMI of ~22 +/- .5 while increasing muscle mass. At the same time, I am reducing fat. Presently, I have a BMI of ~22, and I weigh myself every few days and adjust my calorie intake up or down depending on my scale reading.
I inject Tirzepatide directly into the belly fat I am trying to get rid of. After only 2 weeks, there is a noticeable reduction.
There have been zero side effects, and I plan on taking Tirzepatide indefinitely.
So, many peptides, so little time.
I chose Tirzepatide based on a bit of research:
“Tirzepatide is a dual agonist that targets both the glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors. This dual action is unique compared to traditional GLP-1 RAs, which only target the GLP-1 receptor. The GIP receptor activation by tirzepatide enhances insulin secretion and has additional effects on reducing food intake and body weight, although the exact mechanisms in humans are still being studied.[1-3]
Efficacy:
Tirzepatide has shown superior efficacy in glycemic control and weight loss compared to traditional GLP-1 RAs. In the SURPASS clinical trials, tirzepatide reduced HbA1c by 1.24% to 2.58% and body weight by 5.4 to 11.7 kg, which are unprecedented results for a single agent. A significant proportion of patients achieved normoglycemia and substantial weight loss.[1][4-5] Tirzepatide was more effective than semaglutide, a leading GLP-1 RA, in reducing both HbA1c and body weight.[1][5]”
“A thorough review of the studies that led to tirzepatide’s approval allows for comparisons between tirzepatide and GLP-1 RAs; it also allows for predictions of tirzepatide’s eventual place in therapy - an agent used preferentially over GLP-1 RAs in patients with or without diabetes desiring to lose weight.”
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Where are you buying your tirzepatide?
Been on the Retatrutide for almost five weeks. I keep modifying the dose but have used about an average of 2.5mg per week. I love this stuff. I wasn’t even trying to burn fat and it still fell off. I bloat less from cheat meals and still wake up lean the next day. Strength is as high as ever. My face even looks thinner. I’m a believer
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I got mine from Steve Combi. He was offering a special price for Rapamycin News forum members. I don’t know if he is still offering this. DM steve combi @Steve_Combi
you can also get it from peptide suppliers like:
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Rt is my personal go to… I have found it to have fewer side effects and I feel “normal” compared to Tz. Now Tz is also ver effective and over time people do acclimate to it and find their normal with it as well.
After 17 months (8m Tz, 9m Rt) I could not be happier with my weight and the peace of mind that brings.
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Is there a such thing as Ozempic face?
Probably just from weight loss in general.
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Quite so. I do feel normal on both 21 months into using these. I think I’ve landed on using reta for cuts and tirz for maintenance, one reason being that I get hyperesthesia on reta so I don’t like being on it for too long. The other is that tirz is cheaper per mg and I need less of it to get appetite suppression. Even on 12 mg of reta it’s hard to maintain a deficit of more than 15% while doing daily cardio and weights, but I know I’m an outlier.
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I think it’s real but it’s the caloric restriction. Libido is the first thing to go when you slash calories, and a lot of these people are in a rush to drop weight fast. They go way too low on calories and feel horrible.
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