thanks @Virilius . I will note to add it when I place my next order with Indian rep, which is Semaglitude/Wegovy tablets (Need to take few lbs off) . I was always against meds (generally speaking) unless necessary for a medical condition, but now as I approach my middle age of 60-70 
I may need to rethink my stance on medicine. I do start very slow so that should at least provide a bit of a cushion against severe sides.
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I used to dislike meds aswell but nowadays I consider them to be literal miracles.
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I hear you, I’m leaning that way also…I’m starting to think that if one can keep glucose and lipids at bay that will account for good chunk of staying healthy (apart from the usual eating healthy and exercise). Then hopefully RAPA will add few years at the end.
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Why increase Rosuvastatin? With your lipid panel, 5 mg for prevention could be enough, at least to begin with. I started with 1.25 mg/d and if there are nontrivial results, I’m going to stick to this dosage.
Ezetimibe as well, even in lower than minimum doses available/suggested (10 mg), seems to yield good results. I’m taking 1.25 mg/d.
You can always increase later, if needed, according to your final target. By the way, there are in commerce rosuvastatin/Ezetimibe combos (or other statins+ezetimibe).
The official sources on the above have been illustrated in another huge thread (Cardiovascular health).
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thanks @mccoy for the suggestion and perhaps I’ll cut it to 2.5mg. Are you sure you are doing Rosuvastatin as opposed to some other statin. Reason I ask is that when I cut the tablet in 4 (20/4=5mg) I can’t imagine being able to cut that into 4 or 5 other pieces. It will probably be invisible to the naked eye
BTW, just as an FYI the reason I started Rosuv was because me LDL was a bit elevated at 104. If I remember correctly, it always used to read at high 80’s in the past so it is not merely for maintenance, it is a bit of a needed solution also.
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Now a random question regarding the HDL, Is there something specific (medicine or supplement) known to increase it. I had it at 46 which I think it is a bit on the low end. Or is it that anything to lower LDL will/might increase HDL?
I believe there is some evidence for some people that using citrus bergamot could help. There other threads mentioning citrus bergamot but l have not read them and others smarter than me probably addressed this topic. A fair amount of bodybuilders use it to increase HDL so take that for what it is worth.
And maybe omega 3’s.
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Then you are buying 20 mg tablets, but there are 5 mg round pills in commerce (for example, crestor), even though they are small ones, they are easily split in four 1.25 mg pieces.
I have followed the threads in this forum attentively and the logic I gathered is that you can minimize risks and optimize results starting by very low doses (strangely, they seem to be pretty effective).
A basic point to be considered , is that a more meaningful metrics, rather than LDL-C would be non-HDL-C, which in your case is 120 mg/dL, which is not bad to start out with (a threshold value of 130 is suggested if no other risk factors are present).
So, since the values are within a reasonable range, it may be better to start with low dosages and check what happens.
I’m in a situation similar to yours, reasonably good lipid panel, never taken drugs previously, but presently convinced of their use, providing the regimen is well optimized for my individual situation. Starting low may allow you to reap benefits without suffering side effects. It is also possible to increase the dosages, or to change statin or other drugs, after checking the results.
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You mentioned that you feel weaker on Rosuvastatin and Empagliflozin. I had the same issue but magnified. When I took 5 mg of Rosuvastatin, even EOD, my muscles felt weak and I felt like an old man. It turns out I was Rosuvastatin intolerant. You may want to try stopping the Rosuvastatin for a week to see if the weakness resolves itself. If so, you could switch to Atorvastatin (which I did) or Bempedoic Acid. I take a triple combo of 5 mg Atorvastatin, Bempedoic Acid and Ezetemibe. My LDL and Apob went from 120 to 48.
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Thanks @DeStrider, from 120 to 48 that’s very impressive. I’ll give it a try and see how it goes.
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Could also be related to empagliflozin. After a few months on empagliflozin I started feeling weak and had to switch to taking it in the evening.
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Try stopping them each in turn to find the culprit.
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I’ve been taking 5mg/day rosuvastatin for 2 weeks now. I’ve felt pretty beat up the past week but it’s hard to attribute that to the statin since I was learning to surf and also been lifting pretty hard. I would consider trying atorvastatin in the future to see if I feel better on it.
Lipids were looking good a few weeks back (triglycerides 44, LDL 83, ApoB 71), so will be interesting to see how rosuva affects them. Also about 2 weeks into a conservative test cyp cycle (260mg/week), so there’s a lot of moving variables.
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I see Atorvastatin at 5mg dose but what was the dose you used for Bempedoic acid and ezetemibe (that had such great results for you)
