Where are you from, I can only offer blood draws in the Netherlands for now. Make a list of the blood markers you’d like tested and I will verify.
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Hi Stijn,
Heb interesse. Hoe kom ik met je in contact?
Hartelijke groet
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Geweldig, ik zal je een berichtje sturen.
Volunteers BE-Antwerpen possible? contact me
If you live close to the border and want to go to a prikpunt in the Netherlands, sure, if not, it’s too much of an ask for you to drive multiple times.
I am absolutely not familair with the market, if you have some insights let me know, according to this post by RapAdmin: How to get a Rapamycin (sirolimus) Blood Level Test there is multiple providers, but I don’t think any of them are using finger pricks, is it worth it?
I only have a single person who actually got back to me after I replied, help is still needed!
If the cost of them can be made low if a person buys a lot of them then yes I think so
many of us would like to map out our response curve, by checking the levels at several times points the first day and then learn what our personal curve looks like life the coming days perhaps up to a full week or two weeks
Above is a pain to do via blood venipuncture draws. But if one could do it oneself from home it would be a totally different thing.
Longevity doctors would probably love to be able to offer such a measurement as part of their programs.
since rapa interest is growing I think the demand for such testing will go up even more over near term
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Basically being able to get personalized curves like this
Bryan Johnson:
Or even like below
Would be of interest
@Rapasailor @Agetron might hsve perspective on which/how many datapoints would be most interesting for people to collect if you could provide color on what it might cost for 3, 5,10, 15 tests or something like that
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So here is my take… because rapamycin is prescribed and covered by my insurance… so are my labcorp tests for sirolimus (aka rapamycin).
Cost is about $95 per blood draw… lavender capped collection tube. I wait a full week and a few days to get my trough (typically under 1 ng/mL - .07 or .03) take my dose 2mg with 5 fluid ounces of GFJ and test after 2 hours. I usually get a 6x’s increase so 12 to 13 ng/mL.
I do this every four months. Next test will be in April. I don’t see a need for multiple test as I am aware of my low and peak.
My last test in January 2024. I used 4mg with GFJ. I wasn’t dure Zydus packed the same punch as rapamune which I was using.
Hi Stijn, kun je mij je contact gegevens sturen. Groet Dirk
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Would there not be value of eg
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being able to do new tests from home whenever you might want to tweak the protocol - or if you were new to rapa and needed to gather all the data you have done so far, would it not have be nice if you could have done it from home?
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not having to wait for the results, but basically be able to see results directly, especially for the throughs, and hence be able to calibrate better if the window between doses is too long or too short
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with multiple tests during the first hours and first 24 hours gain a better understating of how high your peak actually is / vs hoping the one blood test is done at the right time, is with a given dose and grapefruit amount (or other multiplier)
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being able to get a sense of the area under the curve (AUC) of exposure to a given Rapa protocol
Perhaps the home testing could come with an app that can help visualize and also start collecting the data accruals users and giving averages back for different dose/window length/gender/weight profile.
It would take us in the direction of the difference of having just a single fasting glucose measurement not being that helpful vs the value of getting OGTT, CGM/home finger prick and Hb1Ac data combined
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Ik wil meehelpen. Hoor graag hoe en wat in mijn DM!
Sure, I will also start shipping to the US but I worry about regulatory things, I don’t even know if the blood can stay OK for testing for this long, it has to ship across the world, from the US to the Netherlands.
I have done a test with Truediagnostics before, I had to ship from the Netherlands to the US and there was no problem, but maybe it’s different because they do epigenetic tests while I am doing “regular” blood tests, I will explore the US once NL and eventually EU is sorted out, would you be my first US customer? We can just try it out see if it works.
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@RapAdmin recommends the following schedule (Sirolimus Levels in My Blood - #14 by RapAdmin):
- 3 hours after ingestion
- 7 days after ingestion
- 14 days after ingestion
I am also exploring TREGs, which is a proxy of immune function, which Rapamycin users should ideally track, but first Rapamycin!
@Neo regarding the app you mentioned, I think that Rapamycin is still too little to justify the development of an app, but I respect the vision, instead, I could make a programmatically generated PDF based on the results to visualize the Sirolimus levels in the blood for certain periods.
Are you saying we should also measure Hb1Ac at the time of the sirolimus test, that is certainly possible and Hb1Ac is already verified for dry spot blood measurements.
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I now have 4 addresses, a total of 6 people contacted me and 2 didn’t get back to me.
That means including me, we have 5 people, 5 tests each since we need 25.
I have informed everyone involved but I am waiting for supplies for the lab, the finger pricks, and other equipment. I expect to receive this somewhere mid-next week, I will then start sending out the supplies to everyone.
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I was actually only making a analog / comparison to how fasting glucose at one point in time say twice a year is not that helpful - but CGM / or multiple thinger printable even changes in HbA1c provide more info. And that your home testing solution could be impactful in a similarly to understand rapa peaks, valleys and AUC
Home Apo B would probably be more relevant as I use CGM and since HbA1c is an average of 3+ months of glucose exposure that is one of the tests that I am fine getting as part of my quarterly+ blood draws.
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Hoi Stijn, I’m also Dutch and interested
Great, I’ve messaged you!