Great to hear! Of course, Its the entire group of people participating here that make this site great - so he’s really calling out all of us contributing knowledge, perspective and information here.
I think the problem generally is that there is not enough focus on mechanisms. Hence people are thrashing around trying out interventions without any idea as to (for example) cycling of those interventions let alone how to use multiple interventions.
However, it is an interesting video.
@John_Hemming This is a fundamental problem but I think the reason is the science just isn’t ready to comprehend the stunning complexity of biology. And then to add onto how it works we want to know what happens if we change something like a gene or add 30 chemicals to the soup. The fact that people aren’t dying left and right from drugs and supplements speaks to the resilience of our biology more than the advanced science behind our interventions. I lean into caution.
Mice as models. Short video.
This is a good podcast with Brian Kennedy, and covers lots of rapamycin questions people commonly have:
LIVE AMA: Longevity Scientists Answer Your Health & Longevity Questions LIVE
This sums up Rapamycin nicely.