Do ARBs increase cancer risk?

#21

I did recognize my mistake here: Do ARBs increase cancer risk? - #17 by adssx

There’s no “debating game” here. We’re just random people trying to improve our common knowledge and our health. Your attitude does not seem compatible with this goal. Either change your behavior or go away.

#22

Alright, I also want to apologize — if anything I said came across as offensive, please forgive me. That was not my intention.

#23

Thanks. No worries at all. I also apologize if anything I said came as offensive: it wasn’t my goal either. Anyway the evidence we have so far:

Anything else to add to the above @Cole? We should then be able to conclude on the topic based on the available evidence.

1 Like
#24

MR analyses demonstrated causal protective effects of genetically proxied ACEI/ARB use on gastric [odds ratio (OR) =0.834, P<0.001], colorectal (OR =0.900, P=0.006), lung (OR =0.928, P=0.02), breast (OR =0.942, P=0.03), and endometrial cancer (OR =0.900, P=0.006). These causal associations remained consistent in validation and sensitivity analyses. Mediation analyses indicated the causal, protective effects were partially mediated by vascular endothelial growth factor A (VEGF-A), total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C).

1 Like