DMSO Question - safety and availability

#1

I’ve been interested in the various “Do-it-Yourself” mouthwashes and skincreams.

Over the years I’ve experimented with projects like this, for example, Neem toothpaste, when I couldn’t find such a product in the UK.

I have found a chemical supplier in Britain who supplies 99%+ laboratory DMSO at a reasonable price.

  1. would this be safe to ingest, put on skin or use in a mouthwash?

  2. Am I going to get any adverse interest from, for example, drug cops if I do so. I believe chemical suppliers are supposed to report suspicious transactions. (My address is a bit of a giveaway).

Obviously I’d prefer a British supplier to IndiaMart for product safety reasons.

#2

Update: I now found this UK supplier who seem to supply to private individuals with the sort of product I require. (UK only unfortunately)

[Some chemical suppliers in the UK make it clear they will only supply to commercial organisations, to avoid any issues with kitchen drug chemists]

#3

Review the following postings;

#4

Thanks Joseph.

I’ve already read some of the postings, and some of the book you uploaded.

I’m just looking to get answers to Q’s 1 & 2 above.

Transcutol seems to be ridiculously expensive in UK so I am not considering its use currently.

FYI in previous experiments I’ve used ordinary white cream for skin cream bases and edible oils like almond or coconut for mouthwashes. DMSO seems like a better delivery medium so would have superior results.

#5

To question 1: Yes, yes, and yes.

just be clean, e.g. skin or mouth, before application, also any vessel, no plastics, or whatever contamination will be carried along with the DMSO

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#6

Righto @vongehr . I have glass bottles and mixing vessels so I will use those and avoid any plastic containers. Thanks for the information.

#7

I live in the UK and buy two different types of DMSO from Amazon.

I am not someone for drinking it, but I am OK with topical.

#8

What do you use it for?

#9

I buy the 99% cheap stuff from Amazon. I use it on skin, brush teeth with it every night and have ingested. Ingesting makes you stink. Never a side effect besides stink.

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#10

One more question: is it volatile?

That pertains to the “use by” date of homemade products. If it’s volatile I should only make a small batch at a time.

#11

DMSO freezes at 18 deg C, so it is not volatile.

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#12

I just learned that Eucalyptus oil is very potent, too. In some cases at even low concentrations it matches or even exceeds DMSO at higher concentrations, according to ChatGPT (I mostly use ChatGPT rather than bothering with GPT-5-thinking, as the router has gotten better):

Eucalyptus oil / 1,8-cineole has shown large boosts at 1–5% in various models; in some datasets, eucalyptus (and chenopodium) oils produced order-of-magnitude increases (e.g., ~30×) for specific drugs—illustrating that terpenes can match or exceed high-dose DMSO for certain actives, though results are drug-dependent.

(Hopefully that wasn’t an hallucination / misreading by ChatGPT.)

It also doesn’t harm collagen as much as DMSO. DMSO can alter or disrupt collagen fibers.