This was the only post of Ronald Evans when I searched the forum. He’s a wonderful lecturer.
Another quote from him from a video “Nuclear receptors and AMPK” (I’ll link a few vids) is:
“one of the holy grails in medicine is a pill that can offer the benefits of fitness, especially for those that can’t workout.”
People posting in this thread bring up concerning points on cancer related issues with some of the medications.
Hey, someone posted this video here this past week by Joseph Takahashi:
It was a very good discussion. I wanted to expand on this topic as it’s powerful stuff.
IIRC there are no products that directly target CLOCK or BMAL at this time.
However, has anyone tried those various products mentioned in the picture posted?
If so, how was your experience?
I’ve heard various products listed might help things like inflammation, energy, immune system etc.
Seems some of them are banned by wada under - metabolic modulators.
So they are considered very powerful products in performance(sporting) events.
Perhaps powerful for longevity as well.
I’ve heard a lot of good things about metformin, and other biguanides such as phenformin.
Ursolic acid has been talked about here in a more positive light.
Various flavones are well liked.
Heard good things about SR9009.
There could be some bad things also depending on various things as they are powerful molecules.
Listed:
KL001, KS15, Go compound
aicar, metformin
ckI-7, longdaysin, pf-670642, pf-48000567, compounds 1-3
sr1078, sr1001, nobiletin, neoruscogenin, digoxin, ursolic acid, sr3335
gsk4112, gsk2945, sr9009/9011, sr8278, arn5187
Resveratrol, SRT compounds
Well has anyone tried any of these?
I’ve tried metformin and resveratrol. Nobiletin is an interesting citrus nutrient.
I’ve done a deep dive on the research on both of these compounds using ChatGPT5 Deep Research:
SR9009 study summaries.pdf (49.8 KB)
Summarize SR9011 studies.pdf (34.5 KB)
