I would not deny that there are benefits in having lower iron levels with ferritin on an uninflamed basis below 100. However, it is more complex below that and particularly below 75 and it may require a form of cycling.
Noted John.
As I’ve said before I think I have an iron absorption problem (maybe allied to gluten sensitivity, based on SNPs I have).
That said, my HsCRP remains low so not too concerned
I don’t think we really know exactly where things should lie. It is obvious that there is a point at which it is too low and a point at which it is too high. The level for brain iron looks to be higher than that for anemia. Questions that are hard to answer are the speed to which the reduction in brain levels occurs. Hence you could have a sufficiency in the brain and take ferritin below the maintenance level, but it will take a while before that will affect the brain negatively.
I can understand neurologists wanting higher ferritin, but probably this should guide GPs as well.
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For purely iron-related discussions, I recommend we continue in one of those threads: